Tomei L - Search Results

1

Polypharmacy through Phage Display: Selection of Glucagon and GLP-1 Receptor Co-agonists from a Phage-Displayed Peptide Library.

Demartis A, Lahm A, Tomei L, Beghetto E, Di Biasio V, Orvieto F, Frattolillo F, Carrington PE, Mumick S, Hawes B, Bianchi E, Palani A, Pessi A. Demartis A, et al. Among authors: tomei l. Sci Rep. 2018 Jan 12;8(1):585. doi: 10.1038/s41598-017-18494-5. Sci Rep. 2018. PMID: 29330364 Free PMC article.

2

SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease.

Colarusso S, Ferrigno F, Ponzi S, Pavone F, Conte I, Abate L, Beghetto E, Missineo A, Amaudrut J, Bresciani A, Paonessa G, Tomei L, Montalbetti C, Bianchi E, Toniatti C, Ontoria JM. Colarusso S, et al. Among authors: tomei l. Bioorg Med Chem. 2022 Mar 1;57:116631. doi: 10.1016/j.bmc.2022.116631. Epub 2022 Jan 23. Bioorg Med Chem. 2022. PMID: 35123179

3

2-D Difference in gel electrophoresis combined with Pro-Q Diamond staining: a successful approach for the identification of kinase/phosphatase targets.

Orsatti L, Forte E, Tomei L, Caterino M, Pessi A, Talamo F. Orsatti L, et al. Among authors: tomei l. Electrophoresis. 2009 Jul;30(14):2469-76. doi: 10.1002/elps.200800780. Electrophoresis. 2009. PMID: 19639567

4

High Affinity Binders to EphA2 Isolated from Abdurin Scaffold Libraries; Characterization, Binding and Tumor Targeting.

Ullman C, Mathonet P, Oleksy A, Diamandakis A, Tomei L, Demartis A, Nardi C, Sambucini S, Missineo A, Alt K, Hagemeyer CE, Harris M, Hedt A, Weis R, Gehlsen KR. Ullman C, et al. Among authors: tomei l. PLoS One. 2015 Aug 27;10(8):e0135278. doi: 10.1371/journal.pone.0135278. eCollection 2015. PLoS One. 2015. PMID: 26313909 Free PMC article.

5

Activity of purified hepatitis C virus protease NS3 on peptide substrates.

Steinkühler C, Urbani A, Tomei L, Biasiol G, Sardana M, Bianchi E, Pessi A, De Francesco R. Steinkühler C, et al. Among authors: tomei l. J Virol. 1996 Oct;70(10):6694-700. doi: 10.1128/JVI.70.10.6694-6700.1996. J Virol. 1996. PMID: 8794305 Free PMC article.

6

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).

Bresciani A, Missineo A, Gallo M, Cerretani M, Fezzardi P, Tomei L, Cicero DO, Altamura S, Santoprete A, Ingenito R, Bianchi E, Pacifici R, Dominguez C, Munoz-Sanjuan I, Harper S, Toledo-Sherman L, Park LC. Bresciani A, et al. Among authors: tomei l. Arch Biochem Biophys. 2017 Oct 1;631:31-41. doi: 10.1016/j.abb.2017.08.003. Epub 2017 Aug 8. Arch Biochem Biophys. 2017. PMID: 28801166 Review.

7

A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease.

Tomei L, Failla C, Vitale RL, Bianchi E, De Francesco R. Tomei L, et al. J Gen Virol. 1996 May;77 ( Pt 5):1065-70. doi: 10.1099/0022-1317-77-5-1065. J Gen Virol. 1996. PMID: 8609472

8

Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction.

Colarusso S, De Simone D, Frattarelli T, Andreini M, Cerretani M, Missineo A, Moretti D, Tambone S, Kempf G, Augustin M, Steinbacher S, Munoz-Sanjuan I, Park L, Summa V, Tomei L, Bresciani A, Dominguez C, Toledo-Sherman L, Bianchi E. Colarusso S, et al. Among authors: tomei l. Bioorg Med Chem. 2020 Nov 1;28(21):115738. doi: 10.1016/j.bmc.2020.115738. Epub 2020 Aug 30. Bioorg Med Chem. 2020. PMID: 33065433

9

Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.

Harper S, Avolio S, Pacini B, Di Filippo M, Altamura S, Tomei L, Paonessa G, Di Marco S, Carfi A, Giuliano C, Padron J, Bonelli F, Migliaccio G, De Francesco R, Laufer R, Rowley M, Narjes F. Harper S, et al. Among authors: tomei l. J Med Chem. 2005 Jul 14;48(14):4547-57. doi: 10.1021/jm050056+. J Med Chem. 2005. PMID: 15999993

10

2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp.

Pacini B, Avolio S, Ercolani C, Koch U, Migliaccio G, Narjes F, Pacini L, Tomei L, Harper S. Pacini B, et al. Among authors: tomei l. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6245-9. doi: 10.1016/j.bmcl.2009.06.106. Epub 2009 Jul 17. Bioorg Med Chem Lett. 2009. PMID: 19800789

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