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Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling.
McBride JD, Jenkins AJ, Liu X, Zhang B, Lee K, Berry WL, Janknecht R, Griffin CT, Aston CE, Lyons TJ, Tomasek JJ, Ma JX. McBride JD, et al. Among authors: tomasek jj. J Invest Dermatol. 2014 Jun;134(6):1725-1734. doi: 10.1038/jid.2014.40. Epub 2014 Jan 24. J Invest Dermatol. 2014. PMID: 24463424 Free PMC article.
Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.
Ge Y, Weygant N, Qu D, May R, Berry WL, Yao J, Chandrakesan P, Zheng W, Zhao L, Zhao KL, Drake M, Vega KJ, Bronze MS, Tomasek JJ, An G, Houchen CW. Ge Y, et al. Among authors: tomasek jj. Int J Cancer. 2018 Sep 1;143(5):1162-1175. doi: 10.1002/ijc.31400. Epub 2018 Apr 16. Int J Cancer. 2018. PMID: 29577277 Free PMC article.
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma.
Weygant N, Qu D, May R, Tierney RM, Berry WL, Zhao L, Agarwal S, Chandrakesan P, Chinthalapally HR, Murphy NT, Li JD, Sureban SM, Schlosser MJ, Tomasek JJ, Houchen CW. Weygant N, et al. Among authors: tomasek jj. Oncotarget. 2015 Feb 10;6(4):2193-205. doi: 10.18632/oncotarget.3059. Oncotarget. 2015. PMID: 25605241 Free PMC article.
Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase.
Weygant N, Ge Y, Qu D, Kaddis JS, Berry WL, May R, Chandrakesan P, Bannerman-Menson E, Vega KJ, Tomasek JJ, Bronze MS, An G, Houchen CW. Weygant N, et al. Among authors: tomasek jj. Cancer Res. 2016 Jul 15;76(14):4090-9. doi: 10.1158/0008-5472.CAN-16-0029. Epub 2016 Jun 10. Cancer Res. 2016. PMID: 27287716 Free PMC article.
MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype.
Howard EW, Crider BJ, Updike DL, Bullen EC, Parks EE, Haaksma CJ, Sherry DM, Tomasek JJ. Howard EW, et al. Among authors: tomasek jj. Exp Cell Res. 2012 Aug 1;318(13):1542-53. doi: 10.1016/j.yexcr.2012.03.007. Epub 2012 Mar 17. Exp Cell Res. 2012. PMID: 22449415 Free PMC article.
59 results