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Virus-like nanostructures for tuning immune response.
Mammadov R, Cinar G, Gunduz N, Goktas M, Kayhan H, Tohumeken S, Topal AE, Orujalipoor I, Delibasi T, Dana A, Ide S, Tekinay AB, Guler MO. Mammadov R, et al. Among authors: tohumeken s. Sci Rep. 2015 Nov 18;5:16728. doi: 10.1038/srep16728. Sci Rep. 2015. PMID: 26577983 Free PMC article.
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment.
Hardaker EL, Sanseviero E, Karmokar A, Taylor D, Milo M, Michaloglou C, Hughes A, Mai M, King M, Solanki A, Magiera L, Miragaia R, Kar G, Standifer N, Surace M, Gill S, Peter A, Talbot S, Tohumeken S, Fryer H, Mostafa A, Mulgrew K, Lam C, Hoffmann S, Sutton D, Carnevalli L, Calero-Nieto FJ, Jones GN, Pierce AJ, Wilson Z, Campbell D, Nyoni L, Martins CP, Baker T, Serrano de Almeida G, Ramlaoui Z, Bidar A, Phillips B, Boland J, Iyer S, Barrett JC, Loembé AB, Fuchs SY, Duvvuri U, Lou PJ, Nance MA, Gomez Roca CA, Cadogan E, Critichlow SE, Fawell S, Cobbold M, Dean E, Valge-Archer V, Lau A, Gabrilovich DI, Barry ST. Hardaker EL, et al. Among authors: tohumeken s. Nat Commun. 2024 Feb 24;15(1):1700. doi: 10.1038/s41467-024-45996-4. Nat Commun. 2024. PMID: 38402224 Free PMC article.
Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
Yoo SW, Waheed AA, Deme P, Tohumeken S, Rais R, Smith MD, DeMarino C, Calabresi PA, Kashanchi F, Freed EO, Slusher BS, Haughey NJ. Yoo SW, et al. Among authors: tohumeken s. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2219543120. doi: 10.1073/pnas.2219543120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406092 Free PMC article.