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Page 1
Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C+/- During Development.
Shafaattalab S, Li AY, Jayousi F, Maaref Y, Dababneh S, Hamledari H, Baygi DH, Barszczewski T, Ruprai B, Jannati S, Nagalingam R, Cool AM, Langa P, Chiao M, Roston T, Solaro RJ, Sanatani S, Toepfer C, Lindert S, Lange P, Tibbits GF. Shafaattalab S, et al. Among authors: toepfer c. bioRxiv [Preprint]. 2023 Aug 13:2023.06.06.542948. doi: 10.1101/2023.06.06.542948. bioRxiv. 2023. PMID: 37609317 Free PMC article. Preprint.
Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes.
Robinson P, Sparrow AJ, Psaras Y, Steeples V, Simon JN, Broyles CN, Chang YF, Brook FA, Wang YJ, Blease A, Zhang X, Abassi YA, Geeves MA, Toepfer CN, Watkins H, Redwood C, Daniels MJ. Robinson P, et al. Among authors: toepfer cn. J Mol Cell Cardiol. 2023 Jul;180:44-57. doi: 10.1016/j.yjmcc.2023.04.008. Epub 2023 Apr 29. J Mol Cell Cardiol. 2023. PMID: 37127261 Free PMC article.
Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation.
Venturini G, Alvim JM, Padilha K, Toepfer CN, Gorham JM, Wasson LK, Biagi D, Schenkman S, Carvalho VM, Salgueiro JS, Cardozo KHM, Krieger JE, Pereira AC, Seidman JG, Seidman CE. Venturini G, et al. Among authors: toepfer cn. Front Cell Infect Microbiol. 2023 Feb 6;13:1098457. doi: 10.3389/fcimb.2023.1098457. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36814444 Free PMC article.
Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere.
Agarwal R, Wakimoto H, Paulo JA, Zhang Q, Reichart D, Toepfer C, Sharma A, Tai AC, Lun M, Gorham J, DePalma SR, Gygi SP, Seidman JG, Seidman CE. Agarwal R, et al. Among authors: toepfer c. Circulation. 2022 Nov 29;146(22):1674-1693. doi: 10.1161/CIRCULATIONAHA.122.059688. Epub 2022 Nov 2. Circulation. 2022. PMID: 36321451 Free PMC article.
Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome.
Meier AB, Raj Murthi S, Rawat H, Toepfer CN, Santamaria G, Schmid M, Mastantuono E, Schwarzmayr T, Berutti R, Cleuziou J, Ewert P, Görlach A, Klingel K, Laugwitz KL, Seidman CE, Seidman JG, Moretti A, Wolf CM. Meier AB, et al. Among authors: toepfer cn. iScience. 2021 Dec 9;25(1):103596. doi: 10.1016/j.isci.2021.103596. eCollection 2022 Jan 21. iScience. 2021. PMID: 34988410 Free PMC article.
Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization.
Zhang K, Cloonan PE, Sundaram S, Liu F, Das SL, Ewoldt JK, Bays JL, Tomp S, Toepfer CN, Marsiglia JDC, Gorham J, Reichart D, Eyckmans J, Seidman JG, Seidman CE, Chen CS. Zhang K, et al. Among authors: toepfer cn. Sci Adv. 2021 Oct 15;7(42):eabh3995. doi: 10.1126/sciadv.abh3995. Epub 2021 Oct 15. Sci Adv. 2021. PMID: 34652945 Free PMC article.
Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation.
Agarwal R, Paulo JA, Toepfer CN, Ewoldt JK, Sundaram S, Chopra A, Zhang Q, Gorham J, DePalma SR, Chen CS, Gygi SP, Seidman CE, Seidman JG. Agarwal R, et al. Among authors: toepfer cn. Circ Res. 2021 Sep 17;129(7):751-766. doi: 10.1161/CIRCRESAHA.120.317076. Epub 2021 Aug 18. Circ Res. 2021. PMID: 34405687 Free PMC article.
CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
Psaras Y, Margara F, Cicconet M, Sparrow AJ, Repetti GG, Schmid M, Steeples V, Wilcox JAL, Bueno-Orovio A, Redwood CS, Watkins HC, Robinson P, Rodriguez B, Seidman JG, Seidman CE, Toepfer CN. Psaras Y, et al. Among authors: toepfer cn. Circ Res. 2021 Jul 9;129(2):326-341. doi: 10.1161/CIRCRESAHA.121.318868. Epub 2021 May 21. Circ Res. 2021. PMID: 34018815 Free PMC article.
32 results