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Page 1
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway.
Nishida Y, Nawaz A, Kado T, Takikawa A, Igarashi Y, Onogi Y, Wada T, Sasaoka T, Yamamoto S, Sasahara M, Imura J, Tokuyama K, Usui I, Nakagawa T, Fujisaka S, Kunimasa Y, Tobe K. Nishida Y, et al. Among authors: tobe k. J Cachexia Sarcopenia Muscle. 2020 Feb;11(1):241-258. doi: 10.1002/jcsm.12530. Epub 2020 Jan 31. J Cachexia Sarcopenia Muscle. 2020. PMID: 32003547 Free PMC article.
Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in Irs2(-/-) mice.
Suzuki R, Tobe K, Aoyama M, Inoue A, Sakamoto K, Yamauchi T, Kamon J, Kubota N, Terauchi Y, Yoshimatsu H, Matsuhisa M, Nagasaka S, Ogata H, Tokuyama K, Nagai R, Kadowaki T. Suzuki R, et al. Among authors: tobe k. J Biol Chem. 2004 Jun 11;279(24):25039-49. doi: 10.1074/jbc.M311956200. Epub 2004 Mar 17. J Biol Chem. 2004. PMID: 15028732 Free article.
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways.
Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T. Kubota N, et al. Among authors: tobe k. J Biol Chem. 2006 Mar 31;281(13):8748-55. doi: 10.1074/jbc.M505649200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431926 Free article.
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.
Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T. Kamei N, et al. Among authors: tobe k. J Biol Chem. 2006 Sep 8;281(36):26602-14. doi: 10.1074/jbc.M601284200. Epub 2006 Jun 29. J Biol Chem. 2006. PMID: 16809344 Free article.
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.
Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T. Yamauchi T, et al. Among authors: tobe k. Nat Med. 2007 Mar;13(3):332-9. doi: 10.1038/nm1557. Epub 2007 Feb 1. Nat Med. 2007. PMID: 17268472
Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.
Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T. Kubota N, et al. Among authors: tobe k. Cell Metab. 2008 Jul;8(1):49-64. doi: 10.1016/j.cmet.2008.05.007. Cell Metab. 2008. PMID: 18590692 Free article.
Cloning, bacterial expression, and unique structure of adenosylhomocysteine hydrolase-like protein 1, or inositol 1,4,5-triphosphate receptor-binding protein from mouse kidney.
Gomi T, Takusagawa F, Nishizawa M, Agussalim B, Usui I, Sugiyama E, Taki H, Shinoda K, Hounoki H, Miwa T, Tobe K, Kobayashi M, Ishimoto T, Ogawa H, Mori H. Gomi T, et al. Among authors: tobe k. Biochim Biophys Acta. 2008 Nov;1784(11):1786-94. doi: 10.1016/j.bbapap.2008.08.016. Epub 2008 Sep 5. Biochim Biophys Acta. 2008. PMID: 18804558
Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.
Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T. Watanabe T, et al. Among authors: tobe k. J Biol Chem. 2009 Jan 16;284(3):1803-12. doi: 10.1074/jbc.M807120200. Epub 2008 Nov 13. J Biol Chem. 2009. PMID: 19008231 Free article.
454 results