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The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81.
Witkin JM, Ping X, Cerne R, Mouser C, Jin X, Hobbs J, Tiruveedhula VVNPB, Li G, Jahan R, Rashid F, Kumar Golani L, Cook JM, Smith JL. Witkin JM, et al. Among authors: tiruveedhula vvnpb. Brain Res. 2019 Nov 1;1722:146356. doi: 10.1016/j.brainres.2019.146356. Epub 2019 Jul 29. Brain Res. 2019. PMID: 31369732 Review.
Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease.
Aranđelović J, Santrač A, Batinić B, Todorović L, Stevanović V, Tiruveedhula VVNPB, Sharmin D, Rashid F, Stanojević B, Cook JM, Savić MM. Aranđelović J, et al. Among authors: tiruveedhula vvnpb. CNS Neurosci Ther. 2022 Nov;28(11):1767-1778. doi: 10.1111/cns.13914. Epub 2022 Jul 13. CNS Neurosci Ther. 2022. PMID: 35822698 Free PMC article.
Development of non-sedating antischistosomal benzodiazepines.
Mian MY, Sharmin D, Mondal P, Belayet JB, Hossain MM, McCusker P, Ryan KT, Fedorov AY, Green HA, Ericksen SS, Zamanian M, Tiruveedhula VVNPB, Cook JM, Chan JD. Mian MY, et al. Among authors: tiruveedhula vvnpb. bioRxiv [Preprint]. 2024 Jan 29:2024.01.26.577323. doi: 10.1101/2024.01.26.577323. bioRxiv. 2024. PMID: 38352313 Free PMC article. Preprint.
Vascular effects of midazolam, flumazenil, and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta.
Bojić MG, Treven M, Pandey KP, Tiruveedhula VVNPB, Santrač A, Đukanović Đ, Vojinović N, Amidžić L, Škrbić R, Scholze P, Ernst M, Cook JM, Savić MM. Bojić MG, et al. Among authors: tiruveedhula vvnpb. Can J Physiol Pharmacol. 2024 Mar 1;102(3):206-217. doi: 10.1139/cjpp-2023-0285. Epub 2023 Nov 1. Can J Physiol Pharmacol. 2024. PMID: 37909404
Structural Analogs of the GABAkine KRM-II-81 Are Orally Bioavailable Anticonvulsants without Sedation.
Pandey KP, Divović B, Rashid F, Golani LK, Cerne R, Zahn NM, Meyer MJ, Arnold LA, Sharmin D, Mian MY, Smith JL, Ping X, Jin X, Lippa A, Tiruveedhula VVNPB, Cook JM, Savić MM, Witkin JM. Pandey KP, et al. Among authors: tiruveedhula vvnpb. J Pharmacol Exp Ther. 2023 Apr;385(1):50-61. doi: 10.1124/jpet.122.001362. Epub 2023 Feb 6. J Pharmacol Exp Ther. 2023. PMID: 36746611 Free PMC article.
Hydrochloride Salt of the GABAkine KRM-II-81.
Mian MY, Divović B, Sharmin D, Pandey KP, Golani LK, Tiruveedhula VVNPB, Cerne R, Smith JL, Ping X, Jin X, Imler GH, Deschamps JR, Lippa A, Cook JM, Savić MM, Rowlett J, Witkin JM. Mian MY, et al. Among authors: tiruveedhula vvnpb. ACS Omega. 2022 Jul 27;7(31):27550-27559. doi: 10.1021/acsomega.2c03029. eCollection 2022 Aug 9. ACS Omega. 2022. PMID: 35967038 Free PMC article.
Metabolism, pharmacokinetics, and anticonvulsant activity of a deuterated analog of the α2/3-selective GABAkine KRM-II-81.
Golani LK, Divović B, Sharmin D, Pandey KP, Mian MY, Cerne R, Zahn NM, Meyer MJ, Tiruveedhula VVNPB, Smith JL, Ping X, Jin X, Lippa A, Schkeryantz JM, Arnold LA, Cook JM, Savić MM, Witkin JM. Golani LK, et al. Among authors: tiruveedhula vvnpb. Biopharm Drug Dispos. 2022 Apr;43(2):66-75. doi: 10.1002/bdd.2313. Epub 2022 Mar 10. Biopharm Drug Dispos. 2022. PMID: 35194800
25 results