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Macrophages Guard Endothelial Lineage by Hindering Endothelial-to-Mesenchymal Transition: Implications for the Pathogenesis of Systemic Sclerosis.
Nicolosi PA, Tombetti E, Giovenzana A, Donè E, Pulcinelli E, Meneveri R, Tirone M, Maugeri N, Rovere-Querini P, Manfredi AA, Brunelli S. Nicolosi PA, et al. Among authors: tirone m. J Immunol. 2019 Jul 1;203(1):247-258. doi: 10.4049/jimmunol.1800883. Epub 2019 May 24. J Immunol. 2019. PMID: 31127033 Free article.
High mobility group box 1 orchestrates tissue regeneration via CXCR4.
Tirone M, Tran NL, Ceriotti C, Gorzanelli A, Canepari M, Bottinelli R, Raucci A, Di Maggio S, Santiago C, Mellado M, Saclier M, François S, Careccia G, He M, De Marchis F, Conti V, Ben Larbi S, Cuvellier S, Casalgrandi M, Preti A, Chazaud B, Al-Abed Y, Messina G, Sitia G, Brunelli S, Bianchi ME, Vénéreau E. Tirone M, et al. J Exp Med. 2018 Jan 2;215(1):303-318. doi: 10.1084/jem.20160217. Epub 2017 Dec 4. J Exp Med. 2018. PMID: 29203538 Free PMC article.
Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy.
Careccia G, Saclier M, Tirone M, Ruggieri E, Principi E, Raffaghello L, Torchio S, Recchia D, Canepari M, Gorzanelli A, Ferrara M, Castellani P, Rubartelli A, Rovere-Querini P, Casalgrandi M, Preti A, Lorenzetti I, Bruno C, Bottinelli R, Brunelli S, Previtali SC, Bianchi ME, Messina G, Vénéreau E. Careccia G, et al. Among authors: tirone m. Sci Transl Med. 2021 Jun 2;13(596):eaay8416. doi: 10.1126/scitranslmed.aay8416. Sci Transl Med. 2021. PMID: 34078746
Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment.
De Leo F, Quilici G, Tirone M, De Marchis F, Mannella V, Zucchelli C, Preti A, Gori A, Casalgrandi M, Mezzapelle R, Bianchi ME, Musco G. De Leo F, et al. Among authors: tirone m. EMBO Rep. 2019 Oct 4;20(10):e47788. doi: 10.15252/embr.201947788. Epub 2019 Aug 14. EMBO Rep. 2019. PMID: 31418171 Free PMC article.
24 results