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A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation.
Le Loarer F, Cleven AHG, Bouvier C, Castex MP, Romagosa C, Moreau A, Salas S, Bonhomme B, Gomez-Brouchet A, Laurent C, Le Guellec S, Audard V, Giraud A, Ramos-Oliver I, Cleton-Jansen AM, Savci-Heijink DC, Kroon HM, Baud J, Pissaloux D, Pierron G, Sherwood A, Coindre JM, Bovée JVMG, Larousserie F, Tirode F. Le Loarer F, et al. Among authors: tirode f. Mod Pathol. 2020 Mar;33(3):404-419. doi: 10.1038/s41379-019-0323-8. Epub 2019 Aug 5. Mod Pathol. 2020. PMID: 31383960 Free article.
Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity.
Chibon F, Lagarde P, Salas S, Pérot G, Brouste V, Tirode F, Lucchesi C, de Reynies A, Kauffmann A, Bui B, Terrier P, Bonvalot S, Le Cesne A, Vince-Ranchère D, Blay JY, Collin F, Guillou L, Leroux A, Coindre JM, Aurias A. Chibon F, et al. Among authors: tirode f. Nat Med. 2010 Jul;16(7):781-7. doi: 10.1038/nm.2174. Epub 2010 Jun 27. Nat Med. 2010. PMID: 20581836
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
Postel-Vinay S, Véron AS, Tirode F, Pierron G, Reynaud S, Kovar H, Oberlin O, Lapouble E, Ballet S, Lucchesi C, Kontny U, González-Neira A, Picci P, Alonso J, Patino-Garcia A, de Paillerets BB, Laud K, Dina C, Froguel P, Clavel-Chapelon F, Doz F, Michon J, Chanock SJ, Thomas G, Cox DG, Delattre O. Postel-Vinay S, et al. Among authors: tirode f. Nat Genet. 2012 Feb 12;44(3):323-7. doi: 10.1038/ng.1085. Nat Genet. 2012. PMID: 22327514
A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion.
Pierron G, Tirode F, Lucchesi C, Reynaud S, Ballet S, Cohen-Gogo S, Perrin V, Coindre JM, Delattre O. Pierron G, et al. Among authors: tirode f. Nat Genet. 2012 Mar 4;44(4):461-6. doi: 10.1038/ng.1107. Nat Genet. 2012. PMID: 22387997 Free article.
Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth.
Surdez D, Benetkiewicz M, Perrin V, Han ZY, Pierron G, Ballet S, Lamoureux F, Rédini F, Decouvelaere AV, Daudigeos-Dubus E, Geoerger B, de Pinieux G, Delattre O, Tirode F. Surdez D, et al. Among authors: tirode f. Cancer Res. 2012 Sep 1;72(17):4494-503. doi: 10.1158/0008-5472.CAN-12-0371. Epub 2012 Aug 28. Cancer Res. 2012. PMID: 22930730 Free article.
SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas.
Le Loarer F, Watson S, Pierron G, de Montpreville VT, Ballet S, Firmin N, Auguste A, Pissaloux D, Boyault S, Paindavoine S, Dechelotte PJ, Besse B, Vignaud JM, Brevet M, Fadel E, Richer W, Treilleux I, Masliah-Planchon J, Devouassoux-Shisheboran M, Zalcman G, Allory Y, Bourdeaut F, Thivolet-Bejui F, Ranchere-Vince D, Girard N, Lantuejoul S, Galateau-Sallé F, Coindre JM, Leary A, Delattre O, Blay JY, Tirode F. Le Loarer F, et al. Among authors: tirode f. Nat Genet. 2015 Oct;47(10):1200-5. doi: 10.1038/ng.3399. Epub 2015 Sep 7. Nat Genet. 2015. PMID: 26343384
BAFfling pathologies: Alterations of BAF complexes in cancer.
Arnaud O, Le Loarer F, Tirode F. Arnaud O, et al. Among authors: tirode f. Cancer Lett. 2018 Apr 10;419:266-279. doi: 10.1016/j.canlet.2018.01.046. Epub 2018 Jan 31. Cancer Lett. 2018. PMID: 29374542 Free article. Review.
128 results