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Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes.
Kumar S, Javed R, Mudd M, Pallikkuth S, Lidke KA, Jain A, Tangavelou K, Gudmundsson SR, Ye C, Rusten TE, Anonsen JH, Lystad AH, Claude-Taupin A, Simonsen A, Salemi M, Phinney B, Li J, Guo LW, Bradfute SB, Timmins GS, Eskelinen EL, Deretic V. Kumar S, et al. Among authors: timmins gs. Cell. 2021 Nov 24;184(24):5950-5969.e22. doi: 10.1016/j.cell.2021.10.017. Epub 2021 Nov 5. Cell. 2021. PMID: 34741801 Free PMC article.
Enhancement of lung levels of antibiotics by ambroxol and bromhexine.
Deretic V, Timmins GS. Deretic V, et al. Among authors: timmins gs. Expert Opin Drug Metab Toxicol. 2019 Mar;15(3):213-218. doi: 10.1080/17425255.2019.1578748. Epub 2019 Feb 7. Expert Opin Drug Metab Toxicol. 2019. PMID: 30721101 Free PMC article. Review.
Mechanisms of action of isoniazid.
Timmins GS, Deretic V. Timmins GS, et al. Mol Microbiol. 2006 Dec;62(5):1220-7. doi: 10.1111/j.1365-2958.2006.05467.x. Epub 2006 Oct 27. Mol Microbiol. 2006. PMID: 17074073 Free article. Review.
Ambroxol Induces Autophagy and Potentiates Rifampin Antimycobacterial Activity.
Choi SW, Gu Y, Peters RS, Salgame P, Ellner JJ, Timmins GS, Deretic V. Choi SW, et al. Among authors: timmins gs. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e01019-18. doi: 10.1128/AAC.01019-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 30012752 Free PMC article.
Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.
Chauhan S, Ahmed Z, Bradfute SB, Arko-Mensah J, Mandell MA, Won Choi S, Kimura T, Blanchet F, Waller A, Mudd MH, Jiang S, Sklar L, Timmins GS, Maphis N, Bhaskar K, Piguet V, Deretic V. Chauhan S, et al. Among authors: timmins gs. Nat Commun. 2015 Oct 27;6:8620. doi: 10.1038/ncomms9620. Nat Commun. 2015. PMID: 26503418 Free PMC article.
83 results