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Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease.
Burbano de Lara S, Kemmer S, Biermayer I, Feiler S, Vlasov A, D'Alessandro LA, Helm B, Mölders C, Dieter Y, Ghallab A, Hengstler JG, Körner C, Matz-Soja M, Götz C, Damm G, Hoffmann K, Seehofer D, Berg T, Schilling M, Timmer J, Klingmüller U. Burbano de Lara S, et al. Among authors: timmer j. Mol Syst Biol. 2024 Mar;20(3):187-216. doi: 10.1038/s44320-023-00007-4. Epub 2024 Jan 12. Mol Syst Biol. 2024. PMID: 38216754 Free PMC article.
Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression.
Lucarelli P, Schilling M, Kreutz C, Vlasov A, Boehm ME, Iwamoto N, Steiert B, Lattermann S, Wäsch M, Stepath M, Matter MS, Heikenwälder M, Hoffmann K, Deharde D, Damm G, Seehofer D, Muciek M, Gretz N, Lehmann WD, Timmer J, Klingmüller U. Lucarelli P, et al. Among authors: timmer j. Cell Syst. 2018 Jan 24;6(1):75-89.e11. doi: 10.1016/j.cels.2017.11.010. Epub 2017 Dec 13. Cell Syst. 2018. PMID: 29248373 Free article.
Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction.
Kok F, Rosenblatt M, Teusel M, Nizharadze T, Gonçalves Magalhães V, Dächert C, Maiwald T, Vlasov A, Wäsch M, Tyufekchieva S, Hoffmann K, Damm G, Seehofer D, Boettler T, Binder M, Timmer J, Schilling M, Klingmüller U. Kok F, et al. Among authors: timmer j. Mol Syst Biol. 2020 Jul;16(7):e8955. doi: 10.15252/msb.20198955. Mol Syst Biol. 2020. PMID: 32696599 Free PMC article.
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways.
Klingmüller U, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Götschel F, Hecht A, Walter D, Egger L, Neubert K, Borner C, Brulport M, Schormann W, Sauer C, Baumann F, Preiss R, MacNelly S, Godoy P, Wiercinska E, Ciuclan L, Edelmann J, Zeilinger K, Heinrich M, Zanger UM, Gebhardt R, Maiwald T, Heinrich R, Timmer J, von Weizsäcker F, Hengstler JG. Klingmüller U, et al. Among authors: timmer j. Syst Biol (Stevenage). 2006 Nov;153(6):433-47. doi: 10.1049/ip-syb:20050067. Syst Biol (Stevenage). 2006. PMID: 17186705
Systems biology of JAK/STAT signalling.
Pfeifer AC, Timmer J, Klingmüller U. Pfeifer AC, et al. Among authors: timmer j. Essays Biochem. 2008;45:109-20. doi: 10.1042/BSE0450109. Essays Biochem. 2008. PMID: 18793127 Review.
Model-based extension of high-throughput to high-content data.
Pfeifer AC, Kaschek D, Bachmann J, Klingmüller U, Timmer J. Pfeifer AC, et al. Among authors: timmer j. BMC Syst Biol. 2010 Aug 5;4:106. doi: 10.1186/1752-0509-4-106. BMC Syst Biol. 2010. PMID: 20687942 Free PMC article.
467 results