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Impact of intensive care unit supportive care on the physiology of Ebola virus disease in a universally lethal non-human primate model.
Poliquin G, Funk D, Jones S, Tran K, Ranadheera C, Hagan M, Tierney K, Grolla A, Dhaliwal A, Bello A, Leung A, Nakamura C, Kobasa D, Falzarano D, Garnett L, Bovendo HF, Feldmann H, Kesselman M, Hansen G, Gren J, Risi G, Biondi M, Mortimer T, Racine T, Deschambault Y, Aminian S, Edmonds J, Sourette R, Allan M, Rondeau L, Hadder S, Press C, DeGraff C, Kucas S, Cook BWM, Hancock BJ, Kumar A, Soni R, Schantz D, McKitrick J, Warner B, Griffin BD, Qiu X, Kobinger GP, Safronetz D, Stein D, Cutts T, Kenny J, Soule G, Kozak R, Theriault S, Menec L, Vendramelli R, Higgins S, Liu G, Rahim NM, Kasloff S, Sloan A, He S, Tailor N, Gray M, Strong JE. Poliquin G, et al. Among authors: tierney k. Intensive Care Med Exp. 2019 Sep 13;7(1):54. doi: 10.1186/s40635-019-0268-8. Intensive Care Med Exp. 2019. PMID: 31520194 Free PMC article.
Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques.
Wong G, Qiu X, de La Vega MA, Fernando L, Wei H, Bello A, Fausther-Bovendo H, Audet J, Kroeker A, Kozak R, Tran K, He S, Tierney K, Soule G, Moffat E, Günther S, Gao GF, Strong J, Embury-Hyatt C, Kobinger G. Wong G, et al. Among authors: tierney k. J Infect Dis. 2016 Oct 15;214(suppl 3):S281-S289. doi: 10.1093/infdis/jiw267. Epub 2016 Sep 19. J Infect Dis. 2016. PMID: 27651412 Free PMC article.
Delivering Prolonged Intensive Care to a Non-human Primate: A High Fidelity Animal Model of Critical Illness.
Poliquin PG, Biondi M, Ranadheera C, Hagan M, Bello A, Racine T, Allan M, Funk D, Hansen G, Hancock BJ, Kesselman M, Mortimer T, Kumar A, Jones S, Leung A, Grolla A, Tran KN, Tierney K, Qiu X, Kobasa D, Strong JE. Poliquin PG, et al. Among authors: tierney k. Sci Rep. 2017 Apr 26;7(1):1204. doi: 10.1038/s41598-017-01107-6. Sci Rep. 2017. PMID: 28446775 Free PMC article.
Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines.
Patel A, Reuschel EL, Kraynyak KA, Racine T, Park DH, Scott VL, Audet J, Amante D, Wise MC, Keaton AA, Wong G, Villarreal DO, Walters J, Muthumani K, Shedlock DJ, de La Vega MA, Plyler R, Boyer J, Broderick KE, Yan J, Khan AS, Jones S, Bello A, Soule G, Tran KN, He S, Tierney K, Qiu X, Kobinger GP, Sardesai NY, Weiner DB. Patel A, et al. Among authors: tierney k. J Infect Dis. 2019 Jan 29;219(4):544-555. doi: 10.1093/infdis/jiy537. J Infect Dis. 2019. PMID: 30304515
Modeling Ebola Virus Transmission Using Ferrets.
de La Vega MA, Soule G, Tran KN, Tierney K, He S, Wong G, Qiu X, Kobinger GP. de La Vega MA, et al. Among authors: tierney k. mSphere. 2018 Oct 31;3(5):e00309-18. doi: 10.1128/mSphere.00309-18. mSphere. 2018. PMID: 30381349 Free PMC article.
In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model.
Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, Yan J, Chen J, Muthumani K, Doranz BJ, Saphire EO, Crowe JE, Broderick KE, Kobinger GP, He S, Qiu X, Kobasa D, Humeau L, Sardesai NY, Ahmed R, Weiner DB. Patel A, et al. Among authors: tierney k. Cell Rep. 2018 Nov 13;25(7):1982-1993.e4. doi: 10.1016/j.celrep.2018.10.062. Cell Rep. 2018. PMID: 30428362 Free PMC article.
Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates.
Brannan JM, He S, Howell KA, Prugar LI, Zhu W, Vu H, Shulenin S, Kailasan S, Raina H, Wong G, Rahim MN, Banadyga L, Tierney K, Zhao X, Li Y, Holtsberg FW, Dye JM, Qiu X, Aman MJ. Brannan JM, et al. Among authors: tierney k. Nat Commun. 2019 Jan 10;10(1):105. doi: 10.1038/s41467-018-08040-w. Nat Commun. 2019. PMID: 30631063 Free PMC article.
171 results