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Genome sequence of the recombinant protein production host Pichia pastoris.
De Schutter K, Lin YC, Tiels P, Van Hecke A, Glinka S, Weber-Lehmann J, Rouzé P, Van de Peer Y, Callewaert N. De Schutter K, et al. Among authors: tiels p. Nat Biotechnol. 2009 Jun;27(6):561-6. doi: 10.1038/nbt.1544. Epub 2009 May 24. Nat Biotechnol. 2009. PMID: 19465926
A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes.
Tiels P, Baranova E, Piens K, De Visscher C, Pynaert G, Nerinckx W, Stout J, Fudalej F, Hulpiau P, Tännler S, Geysens S, Van Hecke A, Valevska A, Vervecken W, Remaut H, Callewaert N. Tiels P, et al. Nat Biotechnol. 2012 Dec;30(12):1225-31. doi: 10.1038/nbt.2427. Epub 2012 Nov 18. Nat Biotechnol. 2012. PMID: 23159880
Characterization of Human Recombinant N-Acetylgalactosamine-6-Sulfate Sulfatase Produced in Pichia pastoris as Potential Enzyme for Mucopolysaccharidosis IVA Treatment.
Rodríguez-López A, Pimentel-Vera LN, Espejo-Mojica AJ, Van Hecke A, Tiels P, Tomatsu S, Callewaert N, Alméciga-Díaz CJ. Rodríguez-López A, et al. Among authors: tiels p. J Pharm Sci. 2019 Aug;108(8):2534-2541. doi: 10.1016/j.xphs.2019.03.034. Epub 2019 Apr 5. J Pharm Sci. 2019. PMID: 30959056
Open access to sequence: browsing the Pichia pastoris genome.
Mattanovich D, Callewaert N, Rouzé P, Lin YC, Graf A, Redl A, Tiels P, Gasser B, De Schutter K. Mattanovich D, et al. Among authors: tiels p. Microb Cell Fact. 2009 Oct 16;8:53. doi: 10.1186/1475-2859-8-53. Microb Cell Fact. 2009. PMID: 19835590 Free PMC article.
MET15 as a visual selection marker for Candida albicans.
Viaene J, Tiels P, Logghe M, Dewaele S, Martinet W, Contreras R. Viaene J, et al. Among authors: tiels p. Yeast. 2000 Sep 30;16(13):1205-15. doi: 10.1002/1097-0061(20000930)16:13<1205::AID-YEA615>3.0.CO;2-C. Yeast. 2000. PMID: 10992284
15 results