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An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging.
Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, Shen-Orr SS, Maecker HT, Dekker CL, Wyss-Coray T, Franceschi C, Jojic V, Haddad F, Montoya JG, Wu JC, Davis MM, Furman D. Sayed N, et al. Among authors: tibshirani r. Nat Aging. 2021 Jul;1:598-615. doi: 10.1038/s43587-021-00082-y. Epub 2021 Jul 12. Nat Aging. 2021. PMID: 34888528 Free PMC article.
Flexible covariate effects in the proportional hazards model.
Hastie T, Sleeper L, Tibshirani R. Hastie T, et al. Among authors: tibshirani r. Breast Cancer Res Treat. 1992;22(3):241-50. doi: 10.1007/BF01840837. Breast Cancer Res Treat. 1992. PMID: 1391990 Clinical Trial.
Generalized additive models for medical research.
Hastie T, Tibshirani R. Hastie T, et al. Among authors: tibshirani r. Stat Methods Med Res. 1995 Sep;4(3):187-96. doi: 10.1177/096228029500400302. Stat Methods Med Res. 1995. PMID: 8548102
Supervised harvesting of expression trees.
Hastie T, Tibshirani R, Botstein D, Brown P. Hastie T, et al. Among authors: tibshirani r. Genome Biol. 2001;2(1):RESEARCH0003. doi: 10.1186/gb-2001-2-1-research0003. Epub 2001 Jan 10. Genome Biol. 2001. PMID: 11178280 Free PMC article.
Regularized linear discriminant analysis and its application in microarrays.
Guo Y, Hastie T, Tibshirani R. Guo Y, et al. Among authors: tibshirani r. Biostatistics. 2007 Jan;8(1):86-100. doi: 10.1093/biostatistics/kxj035. Epub 2006 Apr 7. Biostatistics. 2007. PMID: 16603682
This method generalizes the idea of the "nearest shrunken centroids" (NSC) (Tibshirani and others, 2003) into the classical discriminant analysis. ...It is also suitable for feature elimination purpose and can be used as gene selection method. The open source R pack …
This method generalizes the idea of the "nearest shrunken centroids" (NSC) (Tibshirani and others, 2003) into the classical discrimin …
333 results