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The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.
Renner B, Coleman K, Goldberg R, Amura C, Holland-Neidermyer A, Pierce K, Orth HN, Molina H, Ferreira VP, Cortes C, Pangburn MK, Holers VM, Thurman JM. Renner B, et al. Among authors: thurman jm. J Immunol. 2010 Sep 1;185(5):3086-94. doi: 10.4049/jimmunol.1000111. Epub 2010 Jul 30. J Immunol. 2010. PMID: 20675597 Free PMC article.
Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.
Leinhase I, Schmidt OI, Thurman JM, Hossini AM, Rozanski M, Taha ME, Scheffler A, John T, Smith WR, Holers VM, Stahel PF. Leinhase I, et al. Among authors: thurman jm. Exp Neurol. 2006 Jun;199(2):454-64. doi: 10.1016/j.expneurol.2006.01.033. Epub 2006 Mar 20. Exp Neurol. 2006. PMID: 16545803
169 results