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Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages.
Watson CK, Schloesser D, Fundel-Clemens K, Lerner C, Gabler S, Baskaran P, Wohnhaas CT, Dichtl S, Huber HJ, Ask K, Gantner F, Viollet C, Thomas MJ, Ramirez F, Murray PJ, El Kasmi KC. Watson CK, et al. Among authors: thomas mj. Am J Respir Cell Mol Biol. 2023 Apr;68(4):366-380. doi: 10.1165/rcmb.2022-0021OC. Am J Respir Cell Mol Biol. 2023. PMID: 36227799
Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture.
Gindele JA, Kiechle T, Benediktus K, Birk G, Brendel M, Heinemann F, Wohnhaas CT, LeBlanc M, Zhang H, Strulovici-Barel Y, Crystal RG, Thomas MJ, Stierstorfer B, Quast K, Schymeinsky J. Gindele JA, et al. Among authors: thomas mj. Sci Rep. 2020 Apr 10;10(1):6257. doi: 10.1038/s41598-020-63345-5. Sci Rep. 2020. PMID: 32277131 Free PMC article.
Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in a human iPSC-derived air-liquid interface model.
Schruf E, Schroeder V, Le HQ, Schönberger T, Raedel D, Stewart EL, Fundel-Clemens K, Bluhmki T, Weigle S, Schuler M, Thomas MJ, Heilker R, Webster MJ, Dass M, Frick M, Stierstorfer B, Quast K, Garnett JP. Schruf E, et al. Among authors: thomas mj. FASEB J. 2020 Jun;34(6):7825-7846. doi: 10.1096/fj.201902926R. Epub 2020 Apr 16. FASEB J. 2020. PMID: 32297676
IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice.
Koss CK, Wohnhaas CT, Baker JR, Tilp C, Przibilla M, Lerner C, Frey S, Keck M, Williams CMM, Peter D, Ramanujam M, Fine J, Gantner F, Thomas M, Barnes PJ, Donnelly LE, El Kasmi KC. Koss CK, et al. Commun Biol. 2021 Feb 8;4(1):172. doi: 10.1038/s42003-021-01703-3. Commun Biol. 2021. PMID: 33558616 Free PMC article.
An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury.
Le HQ, Hill MA, Kollak I, Keck M, Schroeder V, Wirth J, Skronska-Wasek W, Schruf E, Strobel B, Stahl H, Herrmann FE, Campos AR, Li J, Quast K, Knebel D, Viollet C, Thomas MJ, Lamb D, Garnett JP. Le HQ, et al. Among authors: thomas mj. EMBO Rep. 2021 Aug 4;22(8):e52785. doi: 10.15252/embr.202152785. Epub 2021 Jul 5. EMBO Rep. 2021. PMID: 34224201 Free PMC article.
Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis.
Schloesser D, Lindenthal L, Sauer J, Chung KJ, Chavakis T, Griesser E, Baskaran P, Maier-Habelsberger U, Fundel-Clemens K, Schlotthauer I, Watson CK, Swee LK, Igney F, Park JE, Huber-Lang MS, Thomas MJ, El Kasmi KC, Murray PJ. Schloesser D, et al. Among authors: thomas mj. J Cell Biol. 2023 Feb 6;222(2):e202207097. doi: 10.1083/jcb.202207097. Epub 2022 Dec 2. J Cell Biol. 2023. PMID: 36459066 Free PMC article.
662 results