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Page 1
Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase.
Winter AJ, Khanizeman RN, Barker-Mountford AMC, Devine AJ, Wang L, Song Z, Davies JA, Race PR, Williams C, Simpson TJ, Willis CL, Crump MP. Winter AJ, et al. Among authors: simpson tj. Angew Chem Weinheim Bergstr Ger. 2023 Nov 20;135(47):e202312514. doi: 10.1002/ange.202312514. Epub 2023 Oct 16. Angew Chem Weinheim Bergstr Ger. 2023. PMID: 38515435 Free PMC article.
Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase.
Winter AJ, Khanizeman RN, Barker-Mountford AMC, Devine AJ, Wang L, Song Z, Davies JA, Race PR, Williams C, Simpson TJ, Willis CL, Crump MP. Winter AJ, et al. Among authors: simpson tj. Angew Chem Int Ed Engl. 2023 Nov 20;62(47):e202312514. doi: 10.1002/anie.202312514. Epub 2023 Oct 17. Angew Chem Int Ed Engl. 2023. PMID: 37768840 Free PMC article.
Uncovering biosynthetic relationships between antifungal nonadrides and octadrides.
de Mattos-Shipley KMJ, Spencer CE, Greco C, Heard DM, O'Flynn DE, Dao TT, Song Z, Mulholland NP, Vincent JL, Simpson TJ, Cox RJ, Bailey AM, Willis CL. de Mattos-Shipley KMJ, et al. Among authors: simpson tj. Chem Sci. 2020 Oct 7;11(42):11570-11578. doi: 10.1039/d0sc04309e. Chem Sci. 2020. PMID: 34094403 Free PMC article.
Total Synthesis of Kalimantacin A.
Davies JA, Bull FM, Walker PD, Weir ANM, Lavigne R, Masschelein J, Simpson TJ, Race PR, Crump MP, Willis CL. Davies JA, et al. Among authors: simpson tj. Org Lett. 2020 Aug 21;22(16):6349-6353. doi: 10.1021/acs.orglett.0c02190. Epub 2020 Aug 10. Org Lett. 2020. PMID: 32806153
The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI.
Fage CD, Lathouwers T, Vanmeert M, Gao LJ, Vrancken K, Lammens EM, Weir ANM, Degroote R, Cuppens H, Kosol S, Simpson TJ, Crump MP, Willis CL, Herdewijn P, Lescrinier E, Lavigne R, Anné J, Masschelein J. Fage CD, et al. Among authors: simpson tj. Angew Chem Int Ed Engl. 2020 Jun 22;59(26):10549-10556. doi: 10.1002/anie.201915407. Epub 2020 Apr 14. Angew Chem Int Ed Engl. 2020. PMID: 32208550
88 results