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Drug discovery for heart failure targeting myosin-binding protein C.
Bunch TA, Guhathakurta P, Thompson AR, Lepak VC, Carter AL, Thomas JJ, Thomas DD, Colson BA. Bunch TA, et al. Among authors: thomas dd. J Biol Chem. 2023 Dec;299(12):105369. doi: 10.1016/j.jbc.2023.105369. Epub 2023 Oct 20. J Biol Chem. 2023. PMID: 37865311 Free PMC article.
Enhancing interaction of actin and actin-binding domain 1 of dystrophin with modulators: Toward improved gene therapy for Duchenne muscular dystrophy.
Guhathakurta P, Carter AL, Thompson AR, Kurila D, LaFrence J, Zhang L, Trask JR, Vanderheyden B, Muretta JM, Ervasti JM, Thomas DD. Guhathakurta P, et al. Among authors: thomas dd. J Biol Chem. 2022 Dec;298(12):102675. doi: 10.1016/j.jbc.2022.102675. Epub 2022 Nov 11. J Biol Chem. 2022. PMID: 36372234 Free PMC article.
HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin.
Muretta JM, Rajasekaran D, Blat Y, Little S, Myers M, Nair C, Burdekin B, Yuen SL, Jimenez N, Guhathakurta P, Wilson A, Thompson AR, Surti N, Connors D, Chase P, Harden D, Barbieri CM, Adam L, Thomas DD. Muretta JM, et al. Among authors: thomas dd. SLAS Discov. 2023 Jul;28(5):223-232. doi: 10.1016/j.slasd.2023.06.001. Epub 2023 Jun 10. SLAS Discov. 2023. PMID: 37307989 Free PMC article.
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[No authors listed] [No authors listed] PMID: 36783165
541 results