Thomas A - Search Results

1

Current Status and Future Perspectives on MRNA Drug Manufacturing.

Webb C, Ip S, Bathula NV, Popova P, Soriano SKV, Ly HH, Eryilmaz B, Nguyen Huu VA, Broadhead R, Rabel M, Villamagna I, Abraham S, Raeesi V, Thomas A, Clarke S, Ramsay EC, Perrie Y, Blakney AK. Webb C, et al. Among authors: thomas a. Mol Pharm. 2022 Apr 4;19(4):1047-1058. doi: 10.1021/acs.molpharmaceut.2c00010. Epub 2022 Mar 3. Mol Pharm. 2022. PMID: 35238565 Free article. Review.

2

Manufacturing Considerations for the Development of Lipid Nanoparticles Using Microfluidics.

Roces CB, Lou G, Jain N, Abraham S, Thomas A, Halbert GW, Perrie Y. Roces CB, et al. Among authors: thomas a. Pharmaceutics. 2020 Nov 15;12(11):1095. doi: 10.3390/pharmaceutics12111095. Pharmaceutics. 2020. PMID: 33203082 Free PMC article.

3

Microfluidic Production and Application of Lipid Nanoparticles for Nucleic Acid Transfection.

Thomas A, M Garg S, De Souza RAG, Ouellet E, Tharmarajah G, Reichert D, Ordobadi M, Ip S, Ramsay EC. Thomas A, et al. Methods Mol Biol. 2018;1792:193-203. doi: 10.1007/978-1-4939-7865-6_14. Methods Mol Biol. 2018. PMID: 29797261

4

Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines.

Blakney AK, McKay PF, Hu K, Samnuan K, Jain N, Brown A, Thomas A, Rogers P, Polra K, Sallah H, Yeow J, Zhu Y, Stevens MM, Geall A, Shattock RJ. Blakney AK, et al. Among authors: thomas a. J Control Release. 2021 Oct 10;338:201-210. doi: 10.1016/j.jconrel.2021.08.029. Epub 2021 Aug 18. J Control Release. 2021. PMID: 34418521 Free PMC article.

5

OX40 agonist stimulation increases and sustains humoral and cell-mediated responses to SARS-CoV-2 protein and saRNA vaccines.

Duhen R, Beymer M, Jensen SM, Abbina S, Abraham S, Jain N, Thomas A, Geall AJ, Hu HM, Fox BA, Weinberg AD. Duhen R, et al. Among authors: thomas a. Front Immunol. 2022 Sep 27;13:896310. doi: 10.3389/fimmu.2022.896310. eCollection 2022. Front Immunol. 2022. PMID: 36238275 Free PMC article.

6

Copper-topotecan complexation mediates drug accumulation into liposomes.

Taggar AS, Alnajim J, Anantha M, Thomas A, Webb M, Ramsay E, Bally MB. Taggar AS, et al. Among authors: thomas a. J Control Release. 2006 Aug 10;114(1):78-88. doi: 10.1016/j.jconrel.2006.05.019. Epub 2006 Jun 2. J Control Release. 2006. PMID: 16842880

7

Development of a liposomal nanoparticle formulation of 5-fluorouracil for parenteral administration: formulation design, pharmacokinetics and efficacy.

Thomas AM, Kapanen AI, Hare JI, Ramsay E, Edwards K, Karlsson G, Bally MB. Thomas AM, et al. J Control Release. 2011 Mar 10;150(2):212-9. doi: 10.1016/j.jconrel.2010.11.018. Epub 2010 Nov 19. J Control Release. 2011. PMID: 21094191

8

Transition metal-mediated liposomal encapsulation of irinotecan (CPT-11) stabilizes the drug in the therapeutically active lactone conformation.

Ramsay E, Alnajim J, Anantha M, Taggar A, Thomas A, Edwards K, Karlsson G, Webb M, Bally M. Ramsay E, et al. Among authors: thomas a. Pharm Res. 2006 Dec;23(12):2799-808. doi: 10.1007/s11095-006-9111-5. Epub 2006 Oct 25. Pharm Res. 2006. PMID: 17063397

9

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia.

Mohanty S, Jyotsana N, Sharma A, Kloos A, Gabdoulline R, Othman B, Lai CK, Schottmann R, Mandhania M, Schmoellerl J, Grebien F, Ramsay E, Thomas A, Vornlocher HP, Ganser A, Thol F, Heuser M. Mohanty S, et al. Among authors: thomas a. Cancers (Basel). 2020 Sep 26;12(10):2766. doi: 10.3390/cancers12102766. Cancers (Basel). 2020. PMID: 32993115 Free PMC article.

10

The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model.

Donohue E, Thomas A, Maurer N, Manisali I, Zeisser-Labouebe M, Zisman N, Anderson HJ, Ng SS, Webb M, Bally M, Roberge M. Donohue E, et al. Among authors: thomas a. J Cancer. 2013 Aug 28;4(7):585-96. doi: 10.7150/jca.7030. eCollection 2013. J Cancer. 2013. PMID: 24069069 Free PMC article.

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