Therrien M - Search Results

1

A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene.

Gavory G, Baril C, Laberge G, Bidla G, Koonpaew S, Sonea T, Sauvageau G, Therrien M. Gavory G, et al. Among authors: therrien m. PLoS Genet. 2021 Aug 12;17(8):e1009730. doi: 10.1371/journal.pgen.1009730. eCollection 2021 Aug. PLoS Genet. 2021. PMID: 34383740 Free PMC article.

2

KSR is a scaffold required for activation of the ERK/MAPK module.

Roy F, Laberge G, Douziech M, Ferland-McCollough D, Therrien M. Roy F, et al. Among authors: therrien m. Genes Dev. 2002 Feb 15;16(4):427-38. doi: 10.1101/gad.962902. Genes Dev. 2002. PMID: 11850406 Free PMC article.

3

Bimodal regulation of RAF by CNK in Drosophila.

Douziech M, Roy F, Laberge G, Lefrançois M, Armengod AV, Therrien M. Douziech M, et al. Among authors: therrien m. EMBO J. 2003 Oct 1;22(19):5068-78. doi: 10.1093/emboj/cdg506. EMBO J. 2003. PMID: 14517245 Free PMC article.

4

Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.

Laberge G, Douziech M, Therrien M. Laberge G, et al. Among authors: therrien m. EMBO J. 2005 Feb 9;24(3):487-98. doi: 10.1038/sj.emboj.7600558. Epub 2005 Jan 20. EMBO J. 2005. PMID: 15660123 Free PMC article.

5

Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila.

Baril C, Therrien M. Baril C, et al. Among authors: therrien m. Dev Biol. 2006 Jun 1;294(1):232-45. doi: 10.1016/j.ydbio.2006.02.046. Epub 2006 Apr 4. Dev Biol. 2006. PMID: 16600208 Free article.

6

A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.

Douziech M, Sahmi M, Laberge G, Therrien M. Douziech M, et al. Among authors: therrien m. Genes Dev. 2006 Apr 1;20(7):807-19. doi: 10.1101/gad.1390406. Genes Dev. 2006. PMID: 16600912 Free PMC article.

7

The PP2C Alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila.

Baril C, Sahmi M, Ashton-Beaucage D, Stronach B, Therrien M. Baril C, et al. Among authors: therrien m. Genetics. 2009 Feb;181(2):567-79. doi: 10.1534/genetics.108.096461. Epub 2008 Dec 8. Genetics. 2009. PMID: 19064708 Free PMC article.

8

The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila.

Ashton-Beaucage D, Udell CM, Lavoie H, Baril C, Lefrançois M, Chagnon P, Gendron P, Caron-Lizotte O, Bonneil E, Thibault P, Therrien M. Ashton-Beaucage D, et al. Among authors: therrien m. Cell. 2010 Oct 15;143(2):251-62. doi: 10.1016/j.cell.2010.09.014. Cell. 2010. PMID: 20946983 Free article.

9

Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.

Lavoie H, Thevakumaran N, Gavory G, Li JJ, Padeganeh A, Guiral S, Duchaine J, Mao DY, Bouvier M, Sicheri F, Therrien M. Lavoie H, et al. Among authors: therrien m. Nat Chem Biol. 2013 Jul;9(7):428-36. doi: 10.1038/nchembio.1257. Epub 2013 May 19. Nat Chem Biol. 2013. PMID: 23685672 Free PMC article.

10

A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila.

Ashton-Beaucage D, Udell CM, Gendron P, Sahmi M, Lefrançois M, Baril C, Guenier AS, Duchaine J, Lamarre D, Lemieux S, Therrien M. Ashton-Beaucage D, et al. Among authors: therrien m. PLoS Biol. 2014 Mar 18;12(3):e1001809. doi: 10.1371/journal.pbio.1001809. eCollection 2014 Mar. PLoS Biol. 2014. PMID: 24643257 Free PMC article.

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