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Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.
Bluemn EG, Coleman IM, Lucas JM, Coleman RT, Hernandez-Lopez S, Tharakan R, Bianchi-Frias D, Dumpit RF, Kaipainen A, Corella AN, Yang YC, Nyquist MD, Mostaghel E, Hsieh AC, Zhang X, Corey E, Brown LG, Nguyen HM, Pienta K, Ittmann M, Schweizer M, True LD, Wise D, Rennie PS, Vessella RL, Morrissey C, Nelson PS. Bluemn EG, et al. Among authors: tharakan r. Cancer Cell. 2017 Oct 9;32(4):474-489.e6. doi: 10.1016/j.ccell.2017.09.003. Cancer Cell. 2017. PMID: 29017058 Free PMC article.
The androgen receptor regulates a druggable translational regulon in advanced prostate cancer.
Liu Y, Horn JL, Banda K, Goodman AZ, Lim Y, Jana S, Arora S, Germanos AA, Wen L, Hardin WR, Yang YC, Coleman IM, Tharakan RG, Cai EY, Uo T, Pillai SPS, Corey E, Morrissey C, Chen Y, Carver BS, Plymate SR, Beronja S, Nelson PS, Hsieh AC. Liu Y, et al. Among authors: tharakan rg. Sci Transl Med. 2019 Jul 31;11(503):eaaw4993. doi: 10.1126/scitranslmed.aaw4993. Sci Transl Med. 2019. PMID: 31366581 Free PMC article.
Methotrexate-based PROTACs as DHFR-specific chemical probes.
Rana S, Dranchak P, Dahlin JL, Lamy L, Li W, Oliphant E, Shrimp JH, Rajacharya GH, Tharakan R, Holland DO, Whitten AS, Wilson KM, Singh PK, Durum SK, Tao D, Rai G, Inglese J. Rana S, et al. Among authors: tharakan r. Cell Chem Biol. 2024 Feb 15;31(2):221-233.e14. doi: 10.1016/j.chembiol.2023.09.014. Epub 2023 Oct 23. Cell Chem Biol. 2024. PMID: 37875111 Free article.
Understanding the Human Aging Proteome Using Epidemiological Models.
Ubaida-Mohien C, Moaddel R, Moore Z, Kuo PL, Tharakan R, Tanaka T, Ferrucci L. Ubaida-Mohien C, et al. Among authors: tharakan r. Methods Mol Biol. 2022;2399:173-192. doi: 10.1007/978-1-0716-1831-8_8. Methods Mol Biol. 2022. PMID: 35604557
Proteomics and Epidemiological Models of Human Aging.
Ubaida-Mohien C, Moaddel R, Moore AZ, Kuo PL, Faghri F, Tharakan R, Tanaka T, Nalls MA, Ferrucci L. Ubaida-Mohien C, et al. Among authors: tharakan r. Front Physiol. 2021 May 31;12:674013. doi: 10.3389/fphys.2021.674013. eCollection 2021. Front Physiol. 2021. PMID: 34135771 Free PMC article. Review.
28 results