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Page 1
Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity.
Larson JH, Jin S, Loschi M, Bolivar Wagers S, Thangavelu G, Zaiken MC, McDonald-Hyman C, Saha A, Aguilar EG, Koehn B, Osborn MJ, Panoskaltsis-Mortari A, Macdonald KPA, Hill GR, Murphy WJ, Serody JS, Maillard I, Kean LS, Kim SV, Littman DR, Blazar BR. Larson JH, et al. Among authors: thangavelu g. Am J Transplant. 2023 Aug;23(8):1102-1115. doi: 10.1016/j.ajt.2023.01.030. Epub 2023 Mar 4. Am J Transplant. 2023. PMID: 36878433
The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease.
McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, Kirchmeier AK, Osborn MJ, Hippen KL, Kelekar A, Serody JS, Turka LA, Munn DH, Chi H, Neubert TA, Dustin ML, Blazar BR. McDonald-Hyman C, et al. Among authors: thangavelu g. J Clin Invest. 2018 Oct 1;128(10):4604-4621. doi: 10.1172/JCI95713. Epub 2018 Aug 14. J Clin Invest. 2018. PMID: 30106752 Free PMC article.
Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD.
Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, Iwawaki T, Ting JP, Serody JS, Murphy WJ, Hill GR, Murray PJ, Bronte V, Munn DH, Zeiser R, Blazar BR. Koehn BH, et al. Among authors: thangavelu g. Blood. 2019 Nov 7;134(19):1670-1682. doi: 10.1182/blood.2019001950. Blood. 2019. PMID: 31533918 Free PMC article.
Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality.
Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, van den Brink M, Dong C, Huang S, Zang X, Allison JP, Zeiser R, Blazar BR. Saha A, et al. Among authors: thangavelu g. JCI Insight. 2019 Oct 3;4(19):e127716. doi: 10.1172/jci.insight.127716. JCI Insight. 2019. PMID: 31578305 Free PMC article.
Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease.
Thangavelu G, Du J, Paz KG, Loschi M, Zaiken MC, Flynn R, Taylor PA, Kirchmeier AK, Panoskaltsis-Mortari A, Luznik L, MacDonald KP, Hill GR, Maillard I, Munn DH, Serody JS, Murphy WJ, Miklos D, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Dahlberg C, Miller AT, Blazar BR. Thangavelu G, et al. Blood. 2020 Jan 2;135(1):28-40. doi: 10.1182/blood.2019000032. Blood. 2020. PMID: 31697815 Free PMC article.
Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses.
Thangavelu G, Wang C, Loschi M, Saha A, Osborn MJ, Furlan SN, Aoyama K, McDonald-Hyman C, Aguilar EG, Janesick AS, Chandraratna RA, Refaeli Y, Panoskaltsis-Mortari A, MacDonald KP, Hill GR, Zeiser R, Maillard I, Serody JS, Murphy WJ, Munn DH, Blumberg B, Brown C, Kuchroo V, Kean LS, Hippen KL, Noelle RJ, Blazar BR. Thangavelu G, et al. Blood. 2021 Feb 25;137(8):1090-1103. doi: 10.1182/blood.2020005628. Blood. 2021. PMID: 32976550 Free PMC article.
35 results