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The endocannabinoid system impacts seizures in a mouse model of Dravet syndrome.
Anderson LL, Doohan PT, Hawkins NA, Bahceci D, Garai S, Thakur GA, Kearney JA, Arnold JC. Anderson LL, et al. Among authors: thakur ga. Neuropharmacology. 2022 Mar 1;205:108897. doi: 10.1016/j.neuropharm.2021.108897. Epub 2021 Nov 22. Neuropharmacology. 2022. PMID: 34822817 Free PMC article.
Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model.
Laprairie RB, Bagher AM, Rourke JL, Zrein A, Cairns EA, Kelly MEM, Sinal CJ, Kulkarni PM, Thakur GA, Denovan-Wright EM. Laprairie RB, et al. Among authors: thakur ga. Neuropharmacology. 2019 Jun;151:1-12. doi: 10.1016/j.neuropharm.2019.03.033. Epub 2019 Mar 30. Neuropharmacology. 2019. PMID: 30940536 Free PMC article.
Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant β Subunits Acquire Sensitivity to α7-Selective Positive Allosteric Modulators.
Stokes C, Garai S, Kulkarni AR, Cantwell LN, Noviello CM, Hibbs RE, Horenstein NA, Abboud KA, Thakur GA, Papke RL. Stokes C, et al. Among authors: thakur ga. J Pharmacol Exp Ther. 2019 Aug;370(2):252-268. doi: 10.1124/jpet.119.259499. Epub 2019 Jun 7. J Pharmacol Exp Ther. 2019. PMID: 31175218 Free PMC article.
134 results