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Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54.
Coecke S, Ahr H, Blaauboer BJ, Bremer S, Casati S, Castell J, Combes R, Corvi R, Crespi CL, Cunningham ML, Elaut G, Eletti B, Freidig A, Gennari A, Ghersi-Egea JF, Guillouzo A, Hartung T, Hoet P, Ingelman-Sundberg M, Munn S, Janssens W, Ladstetter B, Leahy D, Long A, Meneguz A, Monshouwer M, Morath S, Nagelkerke F, Pelkonen O, Ponti J, Prieto P, Richert L, Sabbioni E, Schaack B, Steiling W, Testai E, Vericat JA, Worth A. Coecke S, et al. Among authors: testai e. Altern Lab Anim. 2006 Feb;34(1):49-84. doi: 10.1177/026119290603400113. Altern Lab Anim. 2006. PMID: 16522150 No abstract available.
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.
Adler S, Basketter D, Creton S, Pelkonen O, van Benthem J, Zuang V, Andersen KE, Angers-Loustau A, Aptula A, Bal-Price A, Benfenati E, Bernauer U, Bessems J, Bois FY, Boobis A, Brandon E, Bremer S, Broschard T, Casati S, Coecke S, Corvi R, Cronin M, Daston G, Dekant W, Felter S, Grignard E, Gundert-Remy U, Heinonen T, Kimber I, Kleinjans J, Komulainen H, Kreiling R, Kreysa J, Leite SB, Loizou G, Maxwell G, Mazzatorta P, Munn S, Pfuhler S, Phrakonkham P, Piersma A, Poth A, Prieto P, Repetto G, Rogiers V, Schoeters G, Schwarz M, Serafimova R, Tähti H, Testai E, van Delft J, van Loveren H, Vinken M, Worth A, Zaldivar JM. Adler S, et al. Among authors: testai e. Arch Toxicol. 2011 May;85(5):367-485. doi: 10.1007/s00204-011-0693-2. Epub 2011 May 1. Arch Toxicol. 2011. PMID: 21533817 Review.
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop.
Bessems JG, Loizou G, Krishnan K, Clewell HJ 3rd, Bernasconi C, Bois F, Coecke S, Collnot EM, Diembeck W, Farcal LR, Geraets L, Gundert-Remy U, Kramer N, Küsters G, Leite SB, Pelkonen OR, Schröder K, Testai E, Wilk-Zasadna I, Zaldívar-Comenges JM. Bessems JG, et al. Among authors: testai e. Regul Toxicol Pharmacol. 2014 Feb;68(1):119-39. doi: 10.1016/j.yrtph.2013.11.008. Epub 2013 Nov 26. Regul Toxicol Pharmacol. 2014. PMID: 24287156
Biokinetics in repeated-dosing in vitro drug toxicity studies.
Kramer NI, Di Consiglio E, Blaauboer BJ, Testai E. Kramer NI, et al. Among authors: testai e. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):217-24. doi: 10.1016/j.tiv.2015.09.005. Epub 2015 Sep 8. Toxicol In Vitro. 2015. PMID: 26362508
Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearance.
Gouliarmou V, Lostia AM, Coecke S, Bernasconi C, Bessems J, Dorne JL, Ferguson S, Testai E, Remy UG, Brian Houston J, Monshouwer M, Nong A, Pelkonen O, Morath S, Wetmore BA, Worth A, Zanelli U, Zorzoli MC, Whelan M. Gouliarmou V, et al. Among authors: testai e. Toxicol In Vitro. 2018 Dec;53:233-244. doi: 10.1016/j.tiv.2018.08.004. Epub 2018 Aug 9. Toxicol In Vitro. 2018. PMID: 30099088 Free PMC article.
Optimizing drug discovery by Investigative Toxicology: Current and future trends.
Beilmann M, Boonen H, Czich A, Dear G, Hewitt P, Mow T, Newham P, Oinonen T, Pognan F, Roth A, Valentin JP, Van Goethem F, Weaver RJ, Birk B, Boyer S, Caloni F, Chen AE, Corvi R, Cronin MTD, Daneshian M, Ewart LC, Fitzgerald RE, Hamilton GA, Hartung T, Kangas JD, Kramer NI, Leist M, Marx U, Polak S, Rovida C, Testai E, Van der Water B, Vulto P, Steger-Hartmann T. Beilmann M, et al. Among authors: testai e. ALTEX. 2019;36(2):289-313. doi: 10.14573/altex.1808181. Epub 2018 Dec 20. ALTEX. 2019. PMID: 30570669 Free article.
131 results