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Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
RSC Med Chem. 2021 Dec 16;13(2):150-155. doi: 10.1039/d1md00225b. eCollection 2022 Feb 23.
RSC Med Chem. 2021.
PMID: 35308027
Free PMC article.
Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA.
Anso I, Basso LGM, Wang L, Marina A, Páez-Pérez ED, Jäger C, Gavotto F, Tersa M, Perrone S, Contreras FX, Prandi J, Gilleron M, Linster CL, Corzana F, Lowary TL, Trastoy B, Guerin ME.
Anso I, et al. Among authors: tersa m.
Sci Adv. 2021 Oct 15;7(42):eabj4565. doi: 10.1126/sciadv.abj4565. Epub 2021 Oct 15.
Sci Adv. 2021.
PMID: 34652941
Free PMC article.
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Dissecting the Structural and Chemical Determinants of the "Open-to-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria.
Rodrigo-Unzueta A, Ghirardello M, Urresti S, Delso I, Giganti D, Anso I, Trastoy B, Comino N, Tersa M, D'Angelo C, Cifuente JO, Marina A, Liebau J, Mäler L, Chenal A, Albesa-Jové D, Merino P, Guerin ME.
Rodrigo-Unzueta A, et al. Among authors: tersa m.
Biochemistry. 2020 Aug 18;59(32):2934-2945. doi: 10.1021/acs.biochem.0c00376. Epub 2020 Aug 4.
Biochemistry. 2020.
PMID: 32786405
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Unveiling the activation dynamics of a fold-switch bacterial glycosyltransferase by 19F NMR.
Liebau J, Tersa M, Trastoy B, Patrick J, Rodrigo-Unzueta A, Corzana F, Sparrman T, Guerin ME, Mäler L.
Liebau J, et al. Among authors: tersa m.
J Biol Chem. 2020 Jul 17;295(29):9868-9878. doi: 10.1074/jbc.RA120.014162. Epub 2020 May 20.
J Biol Chem. 2020.
PMID: 32434931
Free PMC article.
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The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria.
Tersa M, Raich L, Albesa-Jové D, Trastoy B, Prandi J, Gilleron M, Rovira C, Guerin ME.
Tersa M, et al.
ACS Chem Biol. 2018 Jan 19;13(1):131-140. doi: 10.1021/acschembio.7b00578. Epub 2017 Dec 11.
ACS Chem Biol. 2018.
PMID: 29185694
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Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.
Albesa-Jové D, Svetlíková Z, Tersa M, Sancho-Vaello E, Carreras-González A, Bonnet P, Arrasate P, Eguskiza A, Angala SK, Cifuente JO, Korduláková J, Jackson M, Mikušová K, Guerin ME.
Albesa-Jové D, et al. Among authors: tersa m.
Nat Commun. 2016 Mar 11;7:10906. doi: 10.1038/ncomms10906.
Nat Commun. 2016.
PMID: 26965057
Free PMC article.
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The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.
Albesa-Jové D, Comino N, Tersa M, Mohorko E, Urresti S, Dainese E, Chiarelli LR, Pasca MR, Manganelli R, Makarov V, Riccardi G, Svergun DI, Glockshuber R, Guerin ME.
Albesa-Jové D, et al. Among authors: tersa m.
J Biol Chem. 2015 Dec 25;290(52):31077-89. doi: 10.1074/jbc.M115.677039. Epub 2015 Nov 6.
J Biol Chem. 2015.
PMID: 26546681
Free PMC article.
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Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
Albesa-Jové D, Chiarelli LR, Makarov V, Pasca MR, Urresti S, Mori G, Salina E, Vocat A, Comino N, Mohorko E, Ryabova S, Pfieiffer B, Lopes Ribeiro AL, Rodrigo-Unzueta A, Tersa M, Zanoni G, Buroni S, Altmann KH, Hartkoorn RC, Glockshuber R, Cole ST, Riccardi G, Guerin ME.
Albesa-Jové D, et al. Among authors: tersa m.
ACS Chem Biol. 2014 Jul 18;9(7):1567-75. doi: 10.1021/cb500149m. Epub 2014 Jun 13.
ACS Chem Biol. 2014.
PMID: 24877756
Free article.
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