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Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Jamshidiha M, Lanyon-Hogg T, Sutherell CL, Craven GB, Tersa M, De Vita E, Brustur D, Pérez-Dorado I, Hassan S, Petracca R, Morgan RM, Sanz-Hernández M, Norman JC, Armstrong A, Mann DJ, Cota E, Tate EW. Jamshidiha M, et al. Among authors: tersa m. RSC Med Chem. 2021 Dec 16;13(2):150-155. doi: 10.1039/d1md00225b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308027 Free PMC article.
Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA.
Anso I, Basso LGM, Wang L, Marina A, Páez-Pérez ED, Jäger C, Gavotto F, Tersa M, Perrone S, Contreras FX, Prandi J, Gilleron M, Linster CL, Corzana F, Lowary TL, Trastoy B, Guerin ME. Anso I, et al. Among authors: tersa m. Sci Adv. 2021 Oct 15;7(42):eabj4565. doi: 10.1126/sciadv.abj4565. Epub 2021 Oct 15. Sci Adv. 2021. PMID: 34652941 Free PMC article.
Dissecting the Structural and Chemical Determinants of the "Open-to-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria.
Rodrigo-Unzueta A, Ghirardello M, Urresti S, Delso I, Giganti D, Anso I, Trastoy B, Comino N, Tersa M, D'Angelo C, Cifuente JO, Marina A, Liebau J, Mäler L, Chenal A, Albesa-Jové D, Merino P, Guerin ME. Rodrigo-Unzueta A, et al. Among authors: tersa m. Biochemistry. 2020 Aug 18;59(32):2934-2945. doi: 10.1021/acs.biochem.0c00376. Epub 2020 Aug 4. Biochemistry. 2020. PMID: 32786405
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
Albesa-Jové D, Chiarelli LR, Makarov V, Pasca MR, Urresti S, Mori G, Salina E, Vocat A, Comino N, Mohorko E, Ryabova S, Pfieiffer B, Lopes Ribeiro AL, Rodrigo-Unzueta A, Tersa M, Zanoni G, Buroni S, Altmann KH, Hartkoorn RC, Glockshuber R, Cole ST, Riccardi G, Guerin ME. Albesa-Jové D, et al. Among authors: tersa m. ACS Chem Biol. 2014 Jul 18;9(7):1567-75. doi: 10.1021/cb500149m. Epub 2014 Jun 13. ACS Chem Biol. 2014. PMID: 24877756 Free article.