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The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.
Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA. Lu TT, et al. Among authors: teperino r. Cell Metab. 2018 Jun 5;27(6):1294-1308.e7. doi: 10.1016/j.cmet.2018.04.013. Epub 2018 May 10. Cell Metab. 2018. PMID: 29754954 Free PMC article.
Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.
Teperino R, Amann S, Bayer M, McGee SL, Loipetzberger A, Connor T, Jaeger C, Kammerer B, Winter L, Wiche G, Dalgaard K, Selvaraj M, Gaster M, Lee-Young RS, Febbraio MA, Knauf C, Cani PD, Aberger F, Penninger JM, Pospisilik JA, Esterbauer H. Teperino R, et al. Cell. 2012 Oct 12;151(2):414-26. doi: 10.1016/j.cell.2012.09.021. Cell. 2012. PMID: 23063129 Free article.
Bridging epigenomics and complex disease: the basics.
Teperino R, Lempradl A, Pospisilik JA. Teperino R, et al. Cell Mol Life Sci. 2013 May;70(9):1609-21. doi: 10.1007/s00018-013-1299-z. Epub 2013 Mar 6. Cell Mol Life Sci. 2013. PMID: 23463237 Review.
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.
Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Tung YC, Lam B, Larder R, Yeo GS, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA. Dalgaard K, et al. Among authors: teperino r. Cell. 2016 Jan 28;164(3):353-64. doi: 10.1016/j.cell.2015.12.025. Cell. 2016. PMID: 26824653 Free PMC article.
MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.
Posavec Marjanović M, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M. Posavec Marjanović M, et al. Among authors: teperino r. Nat Struct Mol Biol. 2017 Nov;24(11):902-910. doi: 10.1038/nsmb.3481. Epub 2017 Oct 9. Nat Struct Mol Biol. 2017. PMID: 28991266 Free PMC article.
Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis.
Todoric J, Strobl B, Jais A, Boucheron N, Bayer M, Amann S, Lindroos J, Teperino R, Prager G, Bilban M, Ellmeier W, Krempler F, Müller M, Wagner O, Patsch W, Pospisilik JA, Esterbauer H. Todoric J, et al. Among authors: teperino r. Diabetes. 2011 Jun;60(6):1668-76. doi: 10.2337/db10-1628. Epub 2011 May 2. Diabetes. 2011. PMID: 21536945 Free PMC article.
30 results