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Preclinical development of kinetin as a safe error-prone SARS-CoV-2 antiviral able to attenuate virus-induced inflammation.
Souza TML, Pinho VD, Setim CF, Sacramento CQ, Marcon R, Fintelman-Rodrigues N, Chaves OA, Heller M, Temerozo JR, Ferreira AC, Mattos M, Momo PB, Dias SSG, Gesto JSM, Pereira-Dutra F, Viola JPB, Queiroz-Junior CM, Guimarães LC, Chaves IM, Guimarães PPG, Costa VV, Teixeira MM, Bou-Habib DC, Bozza PT, Aguillón AR, Siqueira-Junior J, Macedo-Junior S, Andrade EL, Fadanni GP, Tolouei SEL, Potrich FB, Santos AA, Marques NF, Calixto JB, Rabi JA. Souza TML, et al. Among authors: temerozo jr. Nat Commun. 2023 Jan 13;14(1):199. doi: 10.1038/s41467-023-35928-z. Nat Commun. 2023. PMID: 36639383 Free PMC article.
Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives.
Santos Fda C, Abreu P, Castro HC, Paixão IC, Cirne-Santos CC, Giongo V, Barbosa JE, Simonetti BR, Garrido V, Bou-Habib DC, Silva Dde O, Batalha PN, Temerozo JR, Souza TM, Nogueira CM, Cunha AC, Rodrigues CR, Ferreira VF, de Souza MC. Santos Fda C, et al. Among authors: temerozo jr. Bioorg Med Chem. 2009 Aug 1;17(15):5476-81. doi: 10.1016/j.bmc.2009.06.037. Epub 2009 Jun 24. Bioorg Med Chem. 2009. PMID: 19581097 Free article.
Protective effect of gedunin on TLR-mediated inflammation by modulation of inflammasome activation and cytokine production: Evidence of a multitarget compound.
Borges PV, Moret KH, Raghavendra NM, Maramaldo Costa TE, Monteiro AP, Carneiro AB, Pacheco P, Temerozo JR, Bou-Habib DC, das Graças Henriques M, Penido C. Borges PV, et al. Among authors: temerozo jr. Pharmacol Res. 2017 Jan;115:65-77. doi: 10.1016/j.phrs.2016.09.015. Epub 2016 Sep 15. Pharmacol Res. 2017. PMID: 27641928
43 results