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NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL.
Del Giudice I, Rossi D, Chiaretti S, Marinelli M, Tavolaro S, Gabrielli S, Laurenti L, Marasca R, Rasi S, Fangazio M, Guarini A, Gaidano G, Foà R. Del Giudice I, et al. Among authors: tavolaro s. Haematologica. 2012 Mar;97(3):437-41. doi: 10.3324/haematol.2011.060129. Epub 2011 Dec 29. Haematologica. 2012. PMID: 22207691 Free PMC article.
Identification of molecular and functional patterns of p53 alterations in chronic lymphocytic leukemia patients in different phases of the disease.
Marinelli M, Peragine N, Di Maio V, Chiaretti S, De Propris MS, Raponi S, Tavolaro S, Mauro FR, Del Giudice I, Guarini A, Foà R. Marinelli M, et al. Among authors: tavolaro s. Haematologica. 2013 Mar;98(3):371-5. doi: 10.3324/haematol.2012.069906. Epub 2012 Sep 14. Haematologica. 2013. PMID: 22983585 Free PMC article.
Behind the scenes of non-nodal MCL: downmodulation of genes involved in actin cytoskeleton organization, cell projection, cell adhesion, tumour invasion, TP53 pathway and mutated status of immunoglobulin heavy chain genes.
Del Giudice I, Messina M, Chiaretti S, Santangelo S, Tavolaro S, De Propris MS, Nanni M, Pescarmona E, Mancini F, Pulsoni A, Martelli M, Di Rocco A, Finolezzi E, Paoloni F, Mauro FR, Cuneo A, Guarini A, Foà R. Del Giudice I, et al. Among authors: tavolaro s. Br J Haematol. 2012 Mar;156(5):601-11. doi: 10.1111/j.1365-2141.2011.08962.x. Epub 2011 Dec 8. Br J Haematol. 2012. PMID: 22150124 Free article.
BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.
Guarini A, Chiaretti S, Tavolaro S, Maggio R, Peragine N, Citarella F, Ricciardi MR, Santangelo S, Marinelli M, De Propris MS, Messina M, Mauro FR, Del Giudice I, Foà R. Guarini A, et al. Among authors: tavolaro s. Blood. 2008 Aug 1;112(3):782-92. doi: 10.1182/blood-2007-12-127688. Epub 2008 May 16. Blood. 2008. PMID: 18487510 Free article.
Gene expression profiling identifies a subset of adult T-cell acute lymphoblastic leukemia with myeloid-like gene features and over-expression of miR-223.
Chiaretti S, Messina M, Tavolaro S, Zardo G, Elia L, Vitale A, Fatica A, Gorello P, Piciocchi A, Scappucci G, Bozzoni I, Fozza C, Candoni A, Guarini A, Foà R. Chiaretti S, et al. Among authors: tavolaro s. Haematologica. 2010 Jul;95(7):1114-21. doi: 10.3324/haematol.2009.015099. Epub 2010 Apr 23. Haematologica. 2010. PMID: 20418243 Free PMC article.
Evaluation of TP53 mutations with the AmpliChip p53 research test in chronic lymphocytic leukemia: correlation with clinical outcome and gene expression profiling.
Chiaretti S, Tavolaro S, Marinelli M, Messina M, Del Giudice I, Mauro FR, Santangelo S, Piciocchi A, Peragine N, Truong S, Patten N, Ghia EM, Torrente I, De Propris MS, Nanni M, Lawrence J, Guarini A, Foà R. Chiaretti S, et al. Among authors: tavolaro s. Genes Chromosomes Cancer. 2011 Apr;50(4):263-74. doi: 10.1002/gcc.20852. Epub 2011 Jan 13. Genes Chromosomes Cancer. 2011. PMID: 21319261
A subset of chronic lymphocytic leukemia patients display reduced levels of PARP1 expression coupled with a defective irradiation-induced apoptosis.
Bacalini MG, Tavolaro S, Peragine N, Marinelli M, Santangelo S, Del Giudice I, Mauro FR, Di Maio V, Ricciardi MR, Caiafa P, Chiaretti S, Foà R, Guarini A, Reale A. Bacalini MG, et al. Among authors: tavolaro s. Exp Hematol. 2012 Mar;40(3):197-206.e1. doi: 10.1016/j.exphem.2011.11.005. Epub 2011 Nov 23. Exp Hematol. 2012. PMID: 22120020 Free article.
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