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Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1.
Kryza T, Khan T, Lovell S, Harrington BS, Yin J, Porazinski S, Pajic M, Koistinen H, Rantala JK, Dreyer T, Magdolen V, Reuning U, He Y, Tate EW, Hooper JD. Kryza T, et al. Among authors: tate ew. Nat Chem Biol. 2021 Jul;17(7):776-783. doi: 10.1038/s41589-021-00783-w. Epub 2021 Apr 15. Nat Chem Biol. 2021. PMID: 33859413
Chemical probes of surface layer biogenesis in Clostridium difficile.
Dang TH, de la Riva L, Fagan RP, Storck EM, Heal WP, Janoir C, Fairweather NF, Tate EW. Dang TH, et al. Among authors: tate ew. ACS Chem Biol. 2010 Mar 19;5(3):279-85. doi: 10.1021/cb9002859. ACS Chem Biol. 2010. PMID: 20067320 Free article.
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Kryza T, Bock N, Lovell S, Rockstroh A, Lehman ML, Lesner A, Panchadsaram J, Silva LM, Srinivasan S, Snell CE, Williams ED, Fazli L, Gleave M, Batra J, Nelson C, Tate EW, Harris J, Hooper JD, Clements JA. Kryza T, et al. Among authors: tate ew. Mol Oncol. 2020 Jan;14(1):105-128. doi: 10.1002/1878-0261.12587. Epub 2019 Nov 28. Mol Oncol. 2020. PMID: 31630475 Free PMC article.
Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer.
Simões BM, Santiago-Gómez A, Chiodo C, Moreira T, Conole D, Lovell S, Alferez D, Eyre R, Spence K, Sarmiento-Castro A, Kohler B, Morisset L, Lanzino M, Andò S, Marangoni E, Sims AH, Tate EW, Howell SJ, Clarke RB. Simões BM, et al. Among authors: tate ew. Oncogene. 2020 Jun;39(25):4896-4908. doi: 10.1038/s41388-020-1335-z. Epub 2020 May 30. Oncogene. 2020. PMID: 32472077 Free PMC article.
Activity-based profiling for drug discovery.
Serwa R, Tate EW. Serwa R, et al. Among authors: tate ew. Chem Biol. 2011 Apr 22;18(4):407-9. doi: 10.1016/j.chembiol.2011.04.002. Chem Biol. 2011. PMID: 21513874 Free article.
194 results