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151 results

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Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.
Gaziano L, Giambartolomei C, Pereira AC, Gaulton A, Posner DC, Swanson SA, Ho YL, Iyengar SK, Kosik NM, Vujkovic M, Gagnon DR, Bento AP, Barrio-Hernandez I, Rönnblom L, Hagberg N, Lundtoft C, Langenberg C, Pietzner M, Valentine D, Gustincich S, Tartaglia GG, Allara E, Surendran P, Burgess S, Zhao JH, Peters JE, Prins BP, Angelantonio ED, Devineni P, Shi Y, Lynch KE, DuVall SL, Garcon H, Thomann LO, Zhou JJ, Gorman BR, Huffman JE, O'Donnell CJ, Tsao PS, Beckham JC, Pyarajan S, Muralidhar S, Huang GD, Ramoni R, Beltrao P, Danesh J, Hung AM, Chang KM, Sun YV, Joseph J, Leach AR, Edwards TL, Cho K, Gaziano JM, Butterworth AS, Casas JP; VA Million Veteran Program COVID-19 Science Initiative. Gaziano L, et al. Among authors: tartaglia gg. Nat Med. 2021 Apr;27(4):668-676. doi: 10.1038/s41591-021-01310-z. Epub 2021 Apr 9. Nat Med. 2021. PMID: 33837377 Free PMC article.
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA.
Valentini P, Pierattini B, Zacco E, Mangoni D, Espinoza S, Webster NA, Andrews B, Carninci P, Tartaglia GG, Pandolfini L, Gustincich S. Valentini P, et al. Among authors: tartaglia gg. Mol Ther Nucleic Acids. 2022 Feb 2;27:1092-1102. doi: 10.1016/j.omtn.2022.01.021. eCollection 2022 Mar 8. Mol Ther Nucleic Acids. 2022. PMID: 35228902 Free PMC article.
Machine learning methods applied to genotyping data capture interactions between single nucleotide variants in late onset Alzheimer's disease.
Arnal Segura M, Bini G, Fernandez Orth D, Samaras E, Kassis M, Aisopos F, Rambla De Argila J, Paliouras G, Garrard P, Giambartolomei C, Tartaglia GG. Arnal Segura M, et al. Among authors: tartaglia gg. Alzheimers Dement (Amst). 2022 Apr 5;14(1):e12300. doi: 10.1002/dad2.12300. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35415203 Free PMC article.
Probing TDP-43 condensation using an in silico designed aptamer.
Zacco E, Kantelberg O, Milanetti E, Armaos A, Panei FP, Gregory J, Jeacock K, Clarke DJ, Chandran S, Ruocco G, Gustincich S, Horrocks MH, Pastore A, Tartaglia GG. Zacco E, et al. Among authors: tartaglia gg. Nat Commun. 2022 Jun 23;13(1):3306. doi: 10.1038/s41467-022-30944-x. Nat Commun. 2022. PMID: 35739092 Free PMC article.
LINE-1 regulates cortical development by acting as long non-coding RNAs.
Mangoni D, Simi A, Lau P, Armaos A, Ansaloni F, Codino A, Damiani D, Floreani L, Di Carlo V, Vozzi D, Persichetti F, Santoro C, Pandolfini L, Tartaglia GG, Sanges R, Gustincich S. Mangoni D, et al. Among authors: tartaglia gg. Nat Commun. 2023 Aug 17;14(1):4974. doi: 10.1038/s41467-023-40743-7. Nat Commun. 2023. PMID: 37591988 Free PMC article.
RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding.
Zacco E, Broglia L, Kurihara M, Monti M, Gustincich S, Pastore A, Plath K, Nagakawa S, Cerase A, Sanchez de Groot N, Tartaglia GG. Zacco E, et al. Among authors: tartaglia gg. Chem Rev. 2024 Apr 24;124(8):4734-4777. doi: 10.1021/acs.chemrev.3c00575. Epub 2024 Apr 5. Chem Rev. 2024. PMID: 38579177 Free PMC article. Review.
Phase separation drives X-chromosome inactivation: a hypothesis.
Cerase A, Armaos A, Neumayer C, Avner P, Guttman M, Tartaglia GG. Cerase A, et al. Among authors: tartaglia gg. Nat Struct Mol Biol. 2019 May;26(5):331-334. doi: 10.1038/s41594-019-0223-0. Nat Struct Mol Biol. 2019. PMID: 31061525 No abstract available.
Single-photon microscopy to study biomolecular condensates.
Perego E, Zappone S, Castagnetti F, Mariani D, Vitiello E, Rupert J, Zacco E, Tartaglia GG, Bozzoni I, Slenders E, Vicidomini G. Perego E, et al. Among authors: tartaglia gg. Nat Commun. 2023 Dec 12;14(1):8224. doi: 10.1038/s41467-023-43969-7. Nat Commun. 2023. PMID: 38086853 Free PMC article.
151 results