Tarasova NI - Search Results

1

Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma.

Lu X, Sabbasani VR, Osei-Amponsa V, Evans CN, King JC, Tarasov SG, Dyba M, Das S, Chan KC, Schwieters CD, Choudhari S, Fromont C, Zhao Y, Tran B, Chen X, Matsuo H, Andresson T, Chari R, Swenson RE, Tarasova NI, Walters KJ. Lu X, et al. Among authors: tarasova ni. Nat Commun. 2021 Dec 16;12(1):7318. doi: 10.1038/s41467-021-27570-4. Nat Commun. 2021. PMID: 34916494 Free PMC article.

2

Transmembrane inhibitors of P-glycoprotein, an ABC transporter.

Tarasova NI, Seth R, Tarasov SG, Kosakowska-Cholody T, Hrycyna CA, Gottesman MM, Michejda CJ. Tarasova NI, et al. J Med Chem. 2005 Jun 2;48(11):3768-75. doi: 10.1021/jm049065t. J Med Chem. 2005. PMID: 15916428

3

Structural analogues of smoothened intracellular loops as potent inhibitors of Hedgehog pathway and cancer cell growth.

Remsberg JR, Lou H, Tarasov SG, Dean M, Tarasova NI. Remsberg JR, et al. Among authors: tarasova ni. J Med Chem. 2007 Sep 6;50(18):4534-8. doi: 10.1021/jm0705657. Epub 2007 Aug 8. J Med Chem. 2007. PMID: 17685505 Free PMC article.

4

Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target.

Timofeeva OA, Gaponenko V, Lockett SJ, Tarasov SG, Jiang S, Michejda CJ, Perantoni AO, Tarasova NI. Timofeeva OA, et al. Among authors: tarasova ni. ACS Chem Biol. 2007 Dec 21;2(12):799-809. doi: 10.1021/cb700186x. ACS Chem Biol. 2007. PMID: 18154267

5

Peptide structure stabilization by membrane anchoring and its general applicability to the development of potent cell-permeable inhibitors.

Johannessen L, Remsberg J, Gaponenko V, Adams KM, Barchi JJ Jr, Tarasov SG, Jiang S, Tarasova NI. Johannessen L, et al. Among authors: tarasova ni. Chembiochem. 2011 Apr 11;12(6):914-21. doi: 10.1002/cbic.201000563. Epub 2011 Mar 1. Chembiochem. 2011. PMID: 21365731 Free PMC article.

6

Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles.

Tarasov SG, Gaponenko V, Howard OM, Chen Y, Oppenheim JJ, Dyba MA, Subramaniam S, Lee Y, Michejda C, Tarasova NI. Tarasov SG, et al. Among authors: tarasova ni. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9798-803. doi: 10.1073/pnas.1014598108. Epub 2011 May 31. Proc Natl Acad Sci U S A. 2011. PMID: 21628584 Free PMC article.

7

Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA.

Timofeeva OA, Chasovskikh S, Lonskaya I, Tarasova NI, Khavrutskii L, Tarasov SG, Zhang X, Korostyshevskiy VR, Cheema A, Zhang L, Dakshanamurthy S, Brown ML, Dritschilo A. Timofeeva OA, et al. Among authors: tarasova ni. J Biol Chem. 2012 Apr 20;287(17):14192-200. doi: 10.1074/jbc.M111.323899. Epub 2012 Feb 29. J Biol Chem. 2012. PMID: 22378781 Free PMC article.

8

Protein purification-free method of binding affinity determination by microscale thermophoresis.

Khavrutskii L, Yeh J, Timofeeva O, Tarasov SG, Pritt S, Stefanisko K, Tarasova N. Khavrutskii L, et al. J Vis Exp. 2013 Aug 15;(78):50541. doi: 10.3791/50541. J Vis Exp. 2013. PMID: 23979559 Free PMC article.

9

GTP-Dependent K-Ras Dimerization.

Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R. Muratcioglu S, et al. Among authors: tarasova ni. Structure. 2015 Jul 7;23(7):1325-35. doi: 10.1016/j.str.2015.04.019. Epub 2015 Jun 4. Structure. 2015. PMID: 26051715 Free PMC article.

10

Mycobacterium tuberculosis copper-regulated protein SocB is an intrinsically disordered protein that folds upon interaction with a synthetic phospholipid bilayer.

Nowicka U, Hoffman M, Randles L, Shi X, Khavrutskii L, Stefanisko K, Tarasova NI, Darwin KH, Walters KJ. Nowicka U, et al. Among authors: tarasova ni. Proteins. 2016 Feb;84(2):193-200. doi: 10.1002/prot.24970. Epub 2015 Dec 29. Proteins. 2016. PMID: 26650755 Free PMC article.

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