Tapia-Rojas C - Search Results

1

How Many Sirtuin Genes Are Out There? Evolution of Sirtuin Genes in Vertebrates With a Description of a New Family Member.

Opazo JC, Vandewege MW, Hoffmann FG, Zavala K, Meléndez C, Luchsinger C, Cavieres VA, Vargas-Chacoff L, Morera FJ, Burgos PV, Tapia-Rojas C, Mardones GA. Opazo JC, et al. Among authors: tapia rojas c. Mol Biol Evol. 2023 Feb 3;40(2):msad014. doi: 10.1093/molbev/msad014. Mol Biol Evol. 2023. PMID: 36656997 Free PMC article.

2

Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents.

Viayna E, Sola I, Bartolini M, De Simone A, Tapia-Rojas C, Serrano FG, Sabaté R, Juárez-Jiménez J, Pérez B, Luque FJ, Andrisano V, Clos MV, Inestrosa NC, Muñoz-Torrero D. Viayna E, et al. J Med Chem. 2014 Mar 27;57(6):2549-67. doi: 10.1021/jm401824w. Epub 2014 Mar 10. J Med Chem. 2014. PMID: 24568372 Free article.

3

Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing.

Inestrosa NC, Tapia-Rojas C, Griffith TN, Carvajal FJ, Benito MJ, Rivera-Dictter A, Alvarez AR, Serrano FG, Hancke JL, Burgos PV, Parodi J, Varela-Nallar L. Inestrosa NC, et al. Transl Psychiatry. 2011 Jul 12;1(7):e20. doi: 10.1038/tp.2011.19. Transl Psychiatry. 2011. PMID: 22832522 Free PMC article.

4

Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy.

Cavieres VA, González A, Muñoz VC, Yefi CP, Bustamante HA, Barraza RR, Tapia-Rojas C, Otth C, Barrera MJ, González C, Mardones GA, Inestrosa NC, Burgos PV. Cavieres VA, et al. PLoS One. 2015 Aug 26;10(8):e0136313. doi: 10.1371/journal.pone.0136313. eCollection 2015. PLoS One. 2015. PMID: 26308941 Free PMC article.

5

Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-β (Aβ)₄₂ peptides.

Tapia-Rojas C, Burgos PV, Inestrosa NC. Tapia-Rojas C, et al. J Neurochem. 2016 Dec;139(6):1175-1191. doi: 10.1111/jnc.13873. J Neurochem. 2016. PMID: 27778356 Free article.

6

Palmitic acid reduces the autophagic flux in hypothalamic neurons by impairing autophagosome-lysosome fusion and endolysosomal dynamics.

Hernández-Cáceres MP, Cereceda K, Hernández S, Li Y, Narro C, Rivera P, Silva P, Ávalos Y, Jara C, Burgos P, Toledo-Valenzuela L, Lagos P, Cifuentes Araneda F, Perez-Leighton C, Bertocchi C, Clegg DJ, Criollo A, Tapia-Rojas C, Burgos PV, Morselli E. Hernández-Cáceres MP, et al. Mol Cell Oncol. 2020 Jul 25;7(5):1789418. doi: 10.1080/23723556.2020.1789418. eCollection 2020. Mol Cell Oncol. 2020. PMID: 32944643 Free PMC article.

7

Mitochondrial Bioenergetics, Redox Balance, and Calcium Homeostasis Dysfunction with Defective Ultrastructure and Quality Control in the Hippocampus of Aged Female C57BL/6J Mice.

Torres AK, Jara C, Llanquinao J, Lira M, Cortés-Díaz D, Tapia-Rojas C. Torres AK, et al. Among authors: tapia rojas c. Int J Mol Sci. 2023 Mar 13;24(6):5476. doi: 10.3390/ijms24065476. Int J Mol Sci. 2023. PMID: 36982549 Free PMC article.

8

GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies.

Pardo E, Barake F, Godoy JA, Oyanadel C, Espinoza S, Metz C, Retamal C, Massardo L, Tapia-Rojas C, Inestrosa NC, Soza A, González A. Pardo E, et al. Mol Neurobiol. 2019 Nov;56(11):7774-7788. doi: 10.1007/s12035-019-1621-3. Epub 2019 May 22. Mol Neurobiol. 2019. PMID: 31119556

9

Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss.

Olesen MA, Torres AK, Jara C, Murphy MP, Tapia-Rojas C. Olesen MA, et al. Redox Biol. 2020 Jul;34:101558. doi: 10.1016/j.redox.2020.101558. Epub 2020 May 5. Redox Biol. 2020. PMID: 32447261 Free PMC article.

10

Age-Dependent Behavioral and Synaptic Dysfunction Impairment Are Improved with Long-Term Andrographolide Administration in Long-Lived Female Degus (Octodon degus).

Oliva CA, Rivera DS, Torres AK, Lindsay CB, Tapia-Rojas C, Bozinovic F, Inestrosa NC. Oliva CA, et al. Among authors: tapia rojas c. Int J Mol Sci. 2023 Jan 6;24(2):1105. doi: 10.3390/ijms24021105. Int J Mol Sci. 2023. PMID: 36674622 Free PMC article.

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