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The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues.
Pilbrow AP, Folkersen L, Pearson JF, Brown CM, McNoe L, Wang NM, Sweet WE, Tang WH, Black MA, Troughton RW, Richards AM, Franco-Cereceda A, Gabrielsen A, Eriksson P, Moravec CS, Cameron VA. Pilbrow AP, et al. PLoS One. 2012;7(6):e39574. doi: 10.1371/journal.pone.0039574. Epub 2012 Jun 29. PLoS One. 2012. PMID: 22768093 Free PMC article.
A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality.
Zhang X, Yoon JY, Morley M, McLendon JM, Mapuskar KA, Gutmann R, Mehdi H, Bloom HL, Dudley SC, Ellinor PT, Shalaby AA, Weiss R, Tang WHW, Moravec CS, Singh M, Taylor AL, Yancy CW, Feldman AM, McNamara DM, Irani K, Spitz DR, Breheny P, Margulies KB, London B, Boudreau RL. Zhang X, et al. Among authors: tang whw. J Clin Invest. 2018 Mar 1;128(3):1154-1163. doi: 10.1172/JCI95710. Epub 2018 Feb 19. J Clin Invest. 2018. PMID: 29457789 Free PMC article.
828 results