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Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis.
Qin L, Cui Y, Yuan T, Chen D, Zhao R, Li S, Jiang Z, Wu Q, Long Y, Wang S, Tang Z, Pan H, Li X, Wei W, Yang J, Luo X, Zhang Z, Tang Q, Liu P, Weinkove R, Yao Y, Qin D, Thiery JP, Li P. Qin L, et al. Among authors: tang q, tang z. Nat Commun. 2022 Oct 13;13(1):6051. doi: 10.1038/s41467-022-33793-w. Nat Commun. 2022. PMID: 36229619 Free PMC article.
DAP10 integration in CAR-T cells enhances the killing of heterogeneous tumors by harnessing endogenous NKG2D.
Li S, Zhao R, Zheng D, Qin L, Cui Y, Li Y, Jiang Z, Zhong M, Shi J, Li M, Wang X, Tang Z, Wu Q, Long Y, Hu D, Wang S, Yao Y, Liu S, Yang LH, Zhang Z, Tang Q, Liu P, Li Y, Li P. Li S, et al. Among authors: tang q, tang z. Mol Ther Oncolytics. 2022 Jun 6;26:15-26. doi: 10.1016/j.omto.2022.06.003. eCollection 2022 Sep 15. Mol Ther Oncolytics. 2022. PMID: 35784403 Free PMC article.
T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity.
Cui Y, Yuan T, Wang Y, Zheng D, Qin L, Li S, Jiang Z, Lin S, Guo W, Wang Z, Liang Z, Li Y, Yao Y, Liu X, Tang Q, Tu HY, Zhang XC, Tang Z, Wong N, Zhang Z, Qin D, Thiery JP, Xu K, Li P. Cui Y, et al. Among authors: tang q, tang z. Cell Rep. 2023 Jul 25;42(7):112797. doi: 10.1016/j.celrep.2023.112797. Epub 2023 Jul 11. Cell Rep. 2023. PMID: 37436890 Free article.
Reactive Oxygen Species-Responsive Delivery of a Notch Inhibitor to Alleviate Nonalcoholic Steatohepatitis by Inhibiting Hepatic de Novo Lipogenesis and Inflammation.
Chen J, Zhang J, Xia Y, Li J, Jia Q, Zhang Z, Jing X, Xu Y, Zou L, Wang L, Song H, Li J, Liu Q, Xiong Y, Tang Q, Chen W, Yang N, Xu H, Li Y, He J. Chen J, et al. Among authors: tang q. Mol Pharm. 2024 May 15. doi: 10.1021/acs.molpharmaceut.4c00070. Online ahead of print. Mol Pharm. 2024. PMID: 38751169
7,158 results