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Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity.
Guo Y, Xie YQ, Gao M, Zhao Y, Franco F, Wenes M, Siddiqui I, Bevilacqua A, Wang H, Yang H, Feng B, Xie X, Sabatel CM, Tschumi B, Chaiboonchoe A, Wang Y, Li W, Xiao W, Held W, Romero P, Ho PC, Tang L. Guo Y, et al. Among authors: tang l. Nat Immunol. 2021 Jun;22(6):746-756. doi: 10.1038/s41590-021-00940-2. Epub 2021 May 24. Nat Immunol. 2021. PMID: 34031618 Free PMC article.
Delivery of STING agonists for adjuvanting subunit vaccines.
Van Herck S, Feng B, Tang L. Van Herck S, et al. Among authors: tang l. Adv Drug Deliv Rev. 2021 Dec;179:114020. doi: 10.1016/j.addr.2021.114020. Epub 2021 Oct 29. Adv Drug Deliv Rev. 2021. PMID: 34756942 Free article. Review.
A redox-responsive prodrug for tumor-targeted glutamine restriction.
Prange CJ, Sayed NYB, Feng B, Goepfert C, Trujillo DO, Hu X, Tang L. Prange CJ, et al. Among authors: tang l. J Control Release. 2024 Apr;368:251-264. doi: 10.1016/j.jconrel.2024.02.031. Epub 2024 Feb 29. J Control Release. 2024. PMID: 38403173 Free article.
Synthetic 3D scaffolds for cancer immunotherapy.
Kurum A, Gao M, Tang L. Kurum A, et al. Among authors: tang l. Curr Opin Biotechnol. 2020 Oct;65:1-8. doi: 10.1016/j.copbio.2019.11.010. Epub 2019 Dec 13. Curr Opin Biotechnol. 2020. PMID: 31838435 Review.
Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion.
Yu YR, Imrichova H, Wang H, Chao T, Xiao Z, Gao M, Rincon-Restrepo M, Franco F, Genolet R, Cheng WC, Jandus C, Coukos G, Jiang YF, Locasale JW, Zippelius A, Liu PS, Tang L, Bock C, Vannini N, Ho PC. Yu YR, et al. Among authors: tang l. Nat Immunol. 2020 Dec;21(12):1540-1551. doi: 10.1038/s41590-020-0793-3. Epub 2020 Oct 5. Nat Immunol. 2020. PMID: 33020660
Regulatory T cells engineered with TCR signaling-responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter.
Eskandari SK, Sulkaj I, Melo MB, Li N, Allos H, Alhaddad JB, Kollar B, Borges TJ, Eskandari AS, Zinter MA, Cai S, Assaker JP, Choi JY, Al Dulaijan BS, Mansouri A, Haik Y, Tannous BA, van Son WJ, Leuvenink HGD, Pomahac B, Riella LV, Tang L, Seelen MAJ, Irvine DJ, Azzi JR. Eskandari SK, et al. Among authors: tang l. Sci Transl Med. 2020 Nov 11;12(569):eaaw4744. doi: 10.1126/scitranslmed.aaw4744. Sci Transl Med. 2020. PMID: 33177180 Free PMC article.
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