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CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia.
He L, Arnold C, Thoma J, Rohde C, Kholmatov M, Garg S, Hsiao CC, Viol L, Zhang K, Sun R, Schmidt C, Janssen M, MacRae T, Huber K, Thiede C, Hébert J, Sauvageau G, Spratte J, Fluhr H, Aust G, Müller-Tidow C, Niehrs C, Pereira G, Hamann J, Tanaka M, Zaugg JB, Pabst C. He L, et al. Among authors: tanaka m. EMBO Mol Med. 2022 Apr 7;14(4):e14990. doi: 10.15252/emmm.202114990. Epub 2022 Mar 7. EMBO Mol Med. 2022. PMID: 35253392 Free PMC article.
Physical biomarkers for human hematopoietic stem and progenitor cells.
Tanaka M, Thoma J, Poisa-Beiro L, Wuchter P, Eckstein V, Dietrich S, Pabst C, Müller-Tidow C, Ohta T, Ho AD. Tanaka M, et al. Cells Dev. 2023 Jun;174:203845. doi: 10.1016/j.cdev.2023.203845. Epub 2023 Apr 26. Cells Dev. 2023. PMID: 37116713 Free article. Review.
HIV-1 Nef Disrupts CD4+ T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface.
Lamas-Murua M, Stolp B, Kaw S, Thoma J, Tsopoulidis N, Trautz B, Ambiel I, Reif T, Arora S, Imle A, Tibroni N, Wu J, Cui G, Stein JV, Tanaka M, Lyck R, Fackler OT. Lamas-Murua M, et al. Among authors: tanaka m. J Immunol. 2018 Nov 1;201(9):2731-2743. doi: 10.4049/jimmunol.1701420. Epub 2018 Sep 26. J Immunol. 2018. PMID: 30257886
Reversible Host-Guest Crosslinks in Supramolecular Hydrogels for On-Demand Mechanical Stimulation of Human Mesenchymal Stem Cells.
Linke P, Munding N, Kimmle E, Kaufmann S, Hayashi K, Nakahata M, Takashima Y, Sano M, Bastmeyer M, Holstein T, Dietrich S, Müller-Tidow C, Harada A, Ho AD, Tanaka M. Linke P, et al. Among authors: tanaka m. Adv Healthc Mater. 2024 Apr;13(10):e2302607. doi: 10.1002/adhm.202302607. Epub 2023 Dec 25. Adv Healthc Mater. 2024. PMID: 38118064
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