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Transient naive reprogramming corrects hiPS cells functionally and epigenetically.
Buckberry S, Liu X, Poppe D, Tan JP, Sun G, Chen J, Nguyen TV, de Mendoza A, Pflueger J, Frazer T, Vargas-Landín DB, Paynter JM, Smits N, Liu N, Ouyang JF, Rossello FJ, Chy HS, Rackham OJL, Laslett AL, Breen J, Faulkner GJ, Nefzger CM, Polo JM, Lister R. Buckberry S, et al. Among authors: tan jp. Nature. 2023 Aug;620(7975):863-872. doi: 10.1038/s41586-023-06424-7. Epub 2023 Aug 16. Nature. 2023. PMID: 37587336 Free PMC article.
Reprogramming roadmap reveals route to human induced trophoblast stem cells.
Liu X, Ouyang JF, Rossello FJ, Tan JP, Davidson KC, Valdes DS, Schröder J, Sun YBY, Chen J, Knaupp AS, Sun G, Chy HS, Huang Z, Pflueger J, Firas J, Tano V, Buckberry S, Paynter JM, Larcombe MR, Poppe D, Choo XY, O'Brien CM, Pastor WA, Chen D, Leichter AL, Naeem H, Tripathi P, Das PP, Grubman A, Powell DR, Laslett AL, David L, Nilsson SK, Clark AT, Lister R, Nefzger CM, Martelotto LG, Rackham OJL, Polo JM. Liu X, et al. Among authors: tan jp. Nature. 2020 Oct;586(7827):101-107. doi: 10.1038/s41586-020-2734-6. Epub 2020 Sep 16. Nature. 2020. PMID: 32939092
Modelling human blastocysts by reprogramming fibroblasts into iBlastoids.
Liu X, Tan JP, Schröder J, Aberkane A, Ouyang JF, Mohenska M, Lim SM, Sun YBY, Chen J, Sun G, Zhou Y, Poppe D, Lister R, Clark AT, Rackham OJL, Zenker J, Polo JM. Liu X, et al. Among authors: tan jp. Nature. 2021 Mar;591(7851):627-632. doi: 10.1038/s41586-021-03372-y. Epub 2021 Mar 17. Nature. 2021. PMID: 33731926
Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment.
Rudraraju R, Gartner MJ, Neil JA, Stout ES, Chen J, Needham EJ, See M, Mackenzie-Kludas C, Yang Lee LY, Wang M, Pointer H, Karavendzas K, Abu-Bonsrah D, Drew D, Yang Sun YB, Tan JP, Sun G, Salavaty A, Charitakis N, Nim HT, Currie PD, Tham WH, Porrello E, Polo JM, Humphrey SJ, Ramialison M, Elliott DA, Subbarao K. Rudraraju R, et al. Among authors: tan jp. Stem Cell Reports. 2023 Jun 13;18(6):1308-1324. doi: 10.1016/j.stemcr.2023.05.007. Stem Cell Reports. 2023. PMID: 37315523 Free PMC article.
Reprogramming fibroblast into human iBlastoids.
Tan JP, Liu X, Polo JM. Tan JP, et al. Nat Protoc. 2024 Apr 17. doi: 10.1038/s41596-024-00984-2. Online ahead of print. Nat Protoc. 2024. PMID: 38632379 Review.
Parallel use of pluripotent human stem cell lung and heart models provide new insights for treatment of SARS-CoV-2.
Rudraraju R, Gartner MJ, Neil JA, Stout ES, Chen J, Needham EJ, See M, Mackenzie-Kludas C, Yang Lee LY, Wang M, Pointer H, Karavendzas K, Abu-Bonsrah D, Drew D, Sun YBY, Tan JP, Sun G, Salavaty A, Charitakis N, Nim HT, Currie PD, Tham WH, Porrello E, Polo J, Humphrey SJ, Ramialison M, Elliott DA, Subbarao K. Rudraraju R, et al. Among authors: tan jp. bioRxiv [Preprint]. 2022 Sep 21:2022.09.20.508614. doi: 10.1101/2022.09.20.508614. bioRxiv. 2022. PMID: 36172136 Free PMC article. Updated. Preprint.
137 results