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Development of anti-HBV agents targeting HBV capsid proteins.
Kobayakawa T, Amano M, Nakayama M, Tsuji K, Ishii T, Miura Y, Shinohara K, Yamamoto K, Matsuoka M, Tamamura H. Kobayakawa T, et al. Among authors: tamamura h. RSC Med Chem. 2023 Aug 24;14(10):1973-1980. doi: 10.1039/d3md00258f. eCollection 2023 Oct 18. RSC Med Chem. 2023. PMID: 37859721
Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment.
Tsuji K, Owusu KB, Kobayakawa T, Wang R, Fujino M, Kaneko M, Yamamoto N, Murakami T, Tamamura H. Tsuji K, et al. Among authors: tamamura h. Bioorg Med Chem. 2020 Jun 1;28(11):115488. doi: 10.1016/j.bmc.2020.115488. Epub 2020 Apr 8. Bioorg Med Chem. 2020. PMID: 32305183
Potent leads based on CA-19L, an anti-HIV active HIV-1 capsid fragment.
Tsuji K, Wang R, Kobayakawa T, Owusu KB, Fujino M, Kaneko M, Yamamoto N, Murakami T, Tamamura H. Tsuji K, et al. Among authors: tamamura h. Bioorg Med Chem. 2021 Jan 15;30:115923. doi: 10.1016/j.bmc.2020.115923. Epub 2020 Dec 7. Bioorg Med Chem. 2021. PMID: 33316719
Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins.
Kobayakawa T, Yokoyama M, Tsuji K, Fujino M, Kurakami M, Onishi T, Boku S, Ishii T, Miura Y, Shinohara K, Kishihara Y, Ohashi N, Kotani O, Murakami T, Sato H, Tamamura H. Kobayakawa T, et al. Among authors: tamamura h. RSC Adv. 2023 Jan 12;13(3):2156-2167. doi: 10.1039/d2ra06837k. eCollection 2023 Jan 6. RSC Adv. 2023. PMID: 36712613 Free PMC article.
Bivalent HIV-1 fusion inhibitors based on peptidomimetics.
Kobayakawa T, Ebihara K, Tsuji K, Kawada T, Fujino M, Honda Y, Ohashi N, Murakami T, Tamamura H. Kobayakawa T, et al. Among authors: tamamura h. Bioorg Med Chem. 2020 Dec 15;28(24):115812. doi: 10.1016/j.bmc.2020.115812. Epub 2020 Oct 9. Bioorg Med Chem. 2020. PMID: 33157478
Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors.
Kobayakawa T, Tsuji K, Konno K, Himeno A, Masuda A, Yang T, Takahashi K, Ishida Y, Ohashi N, Kuwata T, Matsumoto K, Yoshimura K, Sakawaki H, Miura T, Harada S, Matsushita S, Tamamura H. Kobayakawa T, et al. Among authors: tamamura h. J Med Chem. 2021 Feb 11;64(3):1481-1496. doi: 10.1021/acs.jmedchem.0c01153. Epub 2021 Jan 26. J Med Chem. 2021. PMID: 33497209
Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins.
Kobayakawa T, Yokoyama M, Tsuji K, Fujino M, Kurakami M, Boku S, Nakayama M, Kaneko M, Ohashi N, Kotani O, Murakami T, Sato H, Tamamura H. Kobayakawa T, et al. Among authors: tamamura h. Biomolecules. 2021 Feb 3;11(2):208. doi: 10.3390/biom11020208. Biomolecules. 2021. PMID: 33546092 Free PMC article.
276 results