Talpaz M - Search Results

1

SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation.

Ropa J, Saha N, Hu H, Peterson LF, Talpaz M, Muntean AG. Ropa J, et al. Among authors: talpaz m. Haematologica. 2020 Sep 1;105(9):2273-2285. doi: 10.3324/haematol.2019.223883. Haematologica. 2020. PMID: 33054052 Free PMC article.

2

Targets and effectors of the cellular response to aurora kinase inhibitor MK-0457 (VX-680) in imatinib sensitive and resistant chronic myelogenous leukemia.

Donato NJ, Fang D, Sun H, Giannola D, Peterson LF, Talpaz M. Donato NJ, et al. Among authors: talpaz m. Biochem Pharmacol. 2010 Mar 1;79(5):688-97. doi: 10.1016/j.bcp.2009.10.009. Epub 2009 Oct 27. Biochem Pharmacol. 2010. PMID: 19874801

3

Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis.

Kapuria V, Peterson LF, Fang D, Bornmann WG, Talpaz M, Donato NJ. Kapuria V, et al. Among authors: talpaz m. Cancer Res. 2010 Nov 15;70(22):9265-76. doi: 10.1158/0008-5472.CAN-10-1530. Epub 2010 Nov 2. Cancer Res. 2010. PMID: 21045142

4

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.

Sun H, Kapuria V, Peterson LF, Fang D, Bornmann WG, Bartholomeusz G, Talpaz M, Donato NJ. Sun H, et al. Among authors: talpaz m. Blood. 2011 Mar 17;117(11):3151-62. doi: 10.1182/blood-2010-03-276477. Epub 2011 Jan 19. Blood. 2011. PMID: 21248063 Free article.

5

p53 stabilization induces apoptosis in chronic myeloid leukemia blast crisis cells.

Peterson LF, Mitrikeska E, Giannola D, Lui Y, Sun H, Bixby D, Malek SN, Donato NJ, Wang S, Talpaz M. Peterson LF, et al. Among authors: talpaz m. Leukemia. 2011 May;25(5):761-9. doi: 10.1038/leu.2011.7. Epub 2011 Feb 25. Leukemia. 2011. PMID: 21350558

6

Protein cross-linking as a novel mechanism of action of a ubiquitin-activating enzyme inhibitor with anti-tumor activity.

Kapuria V, Peterson LF, Showalter HD, Kirchhoff PD, Talpaz M, Donato NJ. Kapuria V, et al. Among authors: talpaz m. Biochem Pharmacol. 2011 Aug 15;82(4):341-9. doi: 10.1016/j.bcp.2011.05.012. Epub 2011 May 19. Biochem Pharmacol. 2011. PMID: 21621524

7

Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway.

Potu H, Peterson LF, Pal A, Verhaegen M, Cao J, Talpaz M, Donato NJ. Potu H, et al. Among authors: talpaz m. Oncotarget. 2014 Jul 30;5(14):5559-69. doi: 10.18632/oncotarget.2140. Oncotarget. 2014. PMID: 24980819 Free PMC article.

8

Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies.

Peterson LF, Sun H, Liu Y, Potu H, Kandarpa M, Ermann M, Courtney SM, Young M, Showalter HD, Sun D, Jakubowiak A, Malek SN, Talpaz M, Donato NJ. Peterson LF, et al. Among authors: talpaz m. Blood. 2015 Jun 4;125(23):3588-97. doi: 10.1182/blood-2014-10-605584. Epub 2015 Mar 26. Blood. 2015. PMID: 25814533 Free article.

9

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.

Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, Talpaz M, Bixby DL, Sun D, Hess JL, Muntean AG, Maillard I, Cierpicki T, Grembecka J. Borkin D, et al. Among authors: talpaz m. Cancer Cell. 2015 Apr 13;27(4):589-602. doi: 10.1016/j.ccell.2015.02.016. Epub 2015 Mar 26. Cancer Cell. 2015. PMID: 25817203 Free PMC article.

10

Phase 1 dose-finding study of rebastinib (DCC-2036) in patients with relapsed chronic myeloid leukemia and acute myeloid leukemia.

Cortes J, Talpaz M, Smith HP, Snyder DS, Khoury J, Bhalla KN, Pinilla-Ibarz J, Larson R, Mitchell D, Wise SC, Rutkoski TJ, Smith BD, Flynn DL, Kantarjian HM, Rosen O, Van Etten RA. Cortes J, et al. Among authors: talpaz m. Haematologica. 2017 Mar;102(3):519-528. doi: 10.3324/haematol.2016.152710. Epub 2016 Dec 7. Haematologica. 2017. PMID: 27927766 Free PMC article. Clinical Trial.

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