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Systemic treatment with a novel basic fibroblast growth factor mimic small-molecule compound boosts functional recovery after spinal cord injury.
Imagama S, Ogino R, Ueno S, Murayama N, Takemoto N, Shimmyo Y, Kadoshima T, Tamura S, Kuroda M, Matsuyama Y, Kadomatsu K, Morita Y, Inoue T, Ishiguro N. Imagama S, et al. Among authors: takemoto n. PLoS One. 2020 Jul 17;15(7):e0236050. doi: 10.1371/journal.pone.0236050. eCollection 2020. PLoS One. 2020. PMID: 32678832 Free PMC article.
SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer's disease induced by amyloid β and excitatory amino acids.
Ogino R, Murayama N, Noshita T, Takemoto N, Toba T, Oka T, Narii N, Yoshida S, Ueno N, Inoue T. Ogino R, et al. Among authors: takemoto n. Brain Res. 2014 Oct 17;1585:159-66. doi: 10.1016/j.brainres.2014.08.023. Epub 2014 Aug 15. Brain Res. 2014. PMID: 25130662 Free article.
Discovery of (2S)-1-(4-amino-2,3,5- trimethylphenoxy)-3-[4-[4-(4- fluorobenzyl)phenyl]-1-piperazinyl]-2-propanol dimethanesulfonate (SUN N8075): a dual Na(+) and Ca(2+) channel blocker with antioxidant activity.
Annoura H, Nakanishi K, Toba T, Takemoto N, Imajo S, Miyajima A, Tamura-Horikawa Y, Tamura S. Annoura H, et al. Among authors: takemoto n. J Med Chem. 2000 Sep 7;43(18):3372-6. doi: 10.1021/jm000143w. J Med Chem. 2000. PMID: 10978184 No abstract available.
221 results