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Lymphopenia induced by a novel selective S1P(1) antagonist structurally unrelated to S1P.
Fujii Y, Ohtake H, Ono N, Hara T, Sakurai T, Takahashi S, Takayama T, Fukasawa Y, Shiozawa F, Tsukahara N, Hirayama T, Igarashi Y, Goitsuka R. Fujii Y, et al. Among authors: takayama t. Biochim Biophys Acta. 2012 Apr;1821(4):600-6. doi: 10.1016/j.bbalip.2011.12.006. Epub 2011 Dec 30. Biochim Biophys Acta. 2012. PMID: 22265714
Isoquinoline derivatives as potent CRTH2 receptor antagonists: synthesis and SAR.
Nishikawa-Shimono R, Sekiguchi Y, Koami T, Kawamura M, Wakasugi D, Watanabe K, Wakahara S, Matsumoto K, Takayama T. Nishikawa-Shimono R, et al. Among authors: takayama t. Bioorg Med Chem Lett. 2012 May 1;22(9):3305-10. doi: 10.1016/j.bmcl.2012.03.009. Epub 2012 Mar 10. Bioorg Med Chem Lett. 2012. PMID: 22469703
5-(1,3-Benzothiazol-6-yl)-4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazole derivatives as potent and selective transforming growth factor-β type I receptor inhibitors.
Amada H, Sekiguchi Y, Ono N, Koami T, Takayama T, Yabuuchi T, Katakai H, Ikeda A, Aoki M, Naruse T, Wada R, Nozoe A, Sato M. Amada H, et al. Among authors: takayama t. Bioorg Med Chem. 2012 Dec 15;20(24):7128-38. doi: 10.1016/j.bmc.2012.09.066. Epub 2012 Oct 12. Bioorg Med Chem. 2012. PMID: 23117174
Isoquinoline derivatives as potent CRTH2 antagonists: design, synthesis and SAR.
Nishikawa-Shimono R, Sekiguchi Y, Koami T, Kawamura M, Wakasugi D, Watanabe K, Wakahara S, Kimura K, Yamanobe S, Takayama T. Nishikawa-Shimono R, et al. Among authors: takayama t. Bioorg Med Chem. 2013 Dec 15;21(24):7674-85. doi: 10.1016/j.bmc.2013.10.025. Epub 2013 Oct 30. Bioorg Med Chem. 2013. PMID: 24216094
Isoquinoline derivatives as potent, selective, and orally active CRTH2 antagonists.
Nishikawa-Shimono R, Sekiguchi Y, Kawamura M, Wakasugi D, Kawanishi M, Watanabe K, Asakura Y, Takaoka A, Takayama T. Nishikawa-Shimono R, et al. Among authors: takayama t. Chem Pharm Bull (Tokyo). 2014;62(6):528-37. doi: 10.1248/cpb.c13-00980. Chem Pharm Bull (Tokyo). 2014. PMID: 24881658 Free article.
2,037 results