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eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Kashiwagi K, Shichino Y, Osaki T, Sakamoto A, Nishimoto M, Takahashi M, Mito M, Weber F, Ikeuchi Y, Iwasaki S, Ito T. Kashiwagi K, et al. Among authors: takahashi m. Nat Commun. 2021 Dec 7;12(1):7102. doi: 10.1038/s41467-021-27337-x. Nat Commun. 2021. PMID: 34876589 Free PMC article.
RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing.
Kuwasako K, Takahashi M, Unzai S, Tsuda K, Yoshikawa S, He F, Kobayashi N, Güntert P, Shirouzu M, Ito T, Tanaka A, Yokoyama S, Hagiwara M, Kuroyanagi H, Muto Y. Kuwasako K, et al. Among authors: takahashi m. Nat Struct Mol Biol. 2014 Sep;21(9):778-86. doi: 10.1038/nsmb.2870. Epub 2014 Aug 17. Nat Struct Mol Biol. 2014. PMID: 25132178
Crystal structure of eukaryotic translation initiation factor 2B.
Kashiwagi K, Takahashi M, Nishimoto M, Hiyama TB, Higo T, Umehara T, Sakamoto K, Ito T, Yokoyama S. Kashiwagi K, et al. Among authors: takahashi m. Nature. 2016 Mar 3;531(7592):122-5. doi: 10.1038/nature16991. Epub 2016 Feb 22. Nature. 2016. PMID: 26901872
Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment.
Kuwasako K, Nameki N, Tsuda K, Takahashi M, Sato A, Tochio N, Inoue M, Terada T, Kigawa T, Kobayashi N, Shirouzu M, Ito T, Sakamoto T, Wakamatsu K, Güntert P, Takahashi S, Yokoyama S, Muto Y. Kuwasako K, et al. Among authors: takahashi m, takahashi s. Protein Sci. 2017 Feb;26(2):280-291. doi: 10.1002/pro.3080. Epub 2016 Nov 27. Protein Sci. 2017. PMID: 27862552 Free PMC article.
The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.
Iwasaki S, Iwasaki W, Takahashi M, Sakamoto A, Watanabe C, Shichino Y, Floor SN, Fujiwara K, Mito M, Dodo K, Sodeoka M, Imataka H, Honma T, Fukuzawa K, Ito T, Ingolia NT. Iwasaki S, et al. Among authors: takahashi m. Mol Cell. 2019 Feb 21;73(4):738-748.e9. doi: 10.1016/j.molcel.2018.11.026. Epub 2018 Dec 27. Mol Cell. 2019. PMID: 30595437 Free PMC article.
Structural basis for eIF2B inhibition in integrated stress response.
Kashiwagi K, Yokoyama T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Shirouzu M, Ito T. Kashiwagi K, et al. Among authors: takahashi m. Science. 2019 May 3;364(6439):495-499. doi: 10.1126/science.aaw4104. Science. 2019. PMID: 31048492
HCV IRES Captures an Actively Translating 80S Ribosome.
Yokoyama T, Machida K, Iwasaki W, Shigeta T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Harada Y, Shigematsu H, Shirouzu M, Tadakuma H, Imataka H, Ito T. Yokoyama T, et al. Among authors: takahashi m. Mol Cell. 2019 Jun 20;74(6):1205-1214.e8. doi: 10.1016/j.molcel.2019.04.022. Epub 2019 May 9. Mol Cell. 2019. PMID: 31080011 Free article.
Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A.
Chen M, Asanuma M, Takahashi M, Shichino Y, Mito M, Fujiwara K, Saito H, Floor SN, Ingolia NT, Sodeoka M, Dodo K, Ito T, Iwasaki S. Chen M, et al. Among authors: takahashi m. Cell Chem Biol. 2021 Apr 15;28(4):475-486.e8. doi: 10.1016/j.chembiol.2020.11.008. Epub 2020 Dec 8. Cell Chem Biol. 2021. PMID: 33296667 Free PMC article.
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