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Absorption of TAK-491, a new angiotensin II receptor antagonist, in animals.
Kawaguchi N, Ebihara T, Takeuchi T, Morohashi A, Yamasaki H, Tagawa Y, Takahashi J, Kondo T, Asahi S. Kawaguchi N, et al. Among authors: takahashi j. Xenobiotica. 2013 Feb;43(2):182-92. doi: 10.3109/00498254.2012.708797. Epub 2012 Aug 7. Xenobiotica. 2013. PMID: 22867273
UDP-glucuronosyltransferase 2B15 (UGT2B15) is the major enzyme responsible for sipoglitazar glucuronidation in humans: retrospective identification of the UGT isoform by in vitro analysis and the effect of UGT2B15*2 mutation.
Nishihara M, Hiura Y, Kawaguchi N, Takahashi J, Asahi S. Nishihara M, et al. Among authors: takahashi j. Drug Metab Pharmacokinet. 2013;28(6):475-84. doi: 10.2133/dmpk.dmpk-13-rg-004. Epub 2013 May 7. Drug Metab Pharmacokinet. 2013. PMID: 23648677 Free article.
Metabolic fate of sipoglitazar, a novel oral PPAR agonist with activities for PPAR-γ, -α and -δ, in rats and monkeys and comparison with humans in vitro.
Nishihara M, Sudo M, Kamiguchi H, Kawaguchi N, Maeshiba Y, Kiyota Y, Takahashi J, Tagawa Y, Kondo T, Asahi S. Nishihara M, et al. Among authors: takahashi j. Drug Metab Pharmacokinet. 2012;27(2):223-31. doi: 10.2133/dmpk.dmpk-11-rg-061. Epub 2011 Nov 29. Drug Metab Pharmacokinet. 2012. PMID: 22123126 Free article.
Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys.
Yamaoka M, Hara T, Hitaka T, Kaku T, Takeuchi T, Takahashi J, Asahi S, Miki H, Tasaka A, Kusaka M. Yamaoka M, et al. Among authors: takahashi j. J Steroid Biochem Mol Biol. 2012 Apr;129(3-5):115-28. doi: 10.1016/j.jsbmb.2012.01.001. Epub 2012 Jan 12. J Steroid Biochem Mol Biol. 2012. PMID: 22249003
2,430 results