Tabas I - Search Results

1

A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis.

Shi J, Wu X, Wang Z, Li F, Meng Y, Moore RM, Cui J, Xue C, Croce KR, Yurdagul A Jr, Doench JG, Li W, Zarbalis KS, Tabas I, Yamamoto A, Zhang H. Shi J, et al. Among authors: tabas i. Nat Commun. 2022 Dec 24;13(1):7929. doi: 10.1038/s41467-022-35604-8. Nat Commun. 2022. PMID: 36566259 Free PMC article.

2

Efferocytosis in liver disease.

Shi H, Moore MP, Wang X, Tabas I. Shi H, et al. Among authors: tabas i. JHEP Rep. 2023 Nov 16;6(1):100960. doi: 10.1016/j.jhepr.2023.100960. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38234410 Free PMC article. Review.

3

Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis.

Liu W, Yalcinkaya M, Maestre IF, Olszewska M, Ampomah PB, Heimlich JB, Wang R, Vela PS, Xiao T, Bick AG, Levine R, Papapetrou EP, Libby P, Tabas I, Wang N, Tall AR. Liu W, et al. Among authors: tabas i. Nat Cardiovasc Res. 2023 Jun;2(6):572-586. doi: 10.1038/s44161-023-00281-3. Epub 2023 Jun 8. Nat Cardiovasc Res. 2023. PMID: 37539077 Free PMC article.

4

Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers.

Wang X, Moore MP, Shi H, Miyata Y, Donnelly SK, Radiloff DR, Tabas I. Wang X, et al. Among authors: tabas i. Mol Ther Methods Clin Dev. 2023 Nov 23;31:101165. doi: 10.1016/j.omtm.2023.101165. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38144682 Free PMC article.

5

Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH.

Moore MP, Wang X, Shi H, Meroni M, Cherubini A, Ronzoni L, Parks EJ, Ibdah JA, Rector RS, Valenti L, Dongiovanni P, Tabas I. Moore MP, et al. Among authors: tabas i. JHEP Rep. 2023 Feb 26;5(5):100716. doi: 10.1016/j.jhepr.2023.100716. eCollection 2023 May. JHEP Rep. 2023. PMID: 37035456 Free PMC article.

6

A Therapeutically Targetable TAZ-TEAD2 Pathway Drives the Growth of Hepatocellular Carcinoma via ANLN and KIF23.

Saito Y, Yin D, Kubota N, Wang X, Filliol A, Remotti H, Nair A, Fazlollahi L, Hoshida Y, Tabas I, Wangensteen KJ, Schwabe RF. Saito Y, et al. Among authors: tabas i. Gastroenterology. 2023 Jun;164(7):1279-1292. doi: 10.1053/j.gastro.2023.02.043. Epub 2023 Mar 7. Gastroenterology. 2023. PMID: 36894036

7

Efferocytosis-induced lactate enables the proliferation of pro-resolving macrophages to mediate tissue repair.

Ngai D, Schilperoort M, Tabas I. Ngai D, et al. Among authors: tabas i. Nat Metab. 2023 Dec;5(12):2206-2219. doi: 10.1038/s42255-023-00921-9. Epub 2023 Nov 27. Nat Metab. 2023. PMID: 38012414

8

BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis.

Yalcinkaya M, Liu W, Thomas LA, Olszewska M, Xiao T, Abramowicz S, Papapetrou EP, Westerterp M, Wang N, Tabas I, Tall AR. Yalcinkaya M, et al. Among authors: tabas i. Circulation. 2023 Nov 28;148(22):1764-1777. doi: 10.1161/CIRCULATIONAHA.123.065344. Epub 2023 Oct 2. Circulation. 2023. PMID: 37781816

9

Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes.

Dai W, Zhang H, Lund H, Zhang Z, Castleberry M, Rodriguez M, Kuriakose G, Gupta S, Lewandowska M, Powers HR, Valmiki S, Zhu J, Shapiro AD, Hussain MM, López JA, Sorci-Thomas MG, Silverstein RL, Ginsberg HN, Sahoo D, Tabas I, Zheng Z. Dai W, et al. Among authors: tabas i. Science. 2023 Sep;381(6661):eadh5207. doi: 10.1126/science.adh5207. Epub 2023 Sep 1. Science. 2023. PMID: 37651538

10

The role of efferocytosis-fueled macrophage metabolism in the resolution of inflammation.

Schilperoort M, Ngai D, Sukka SR, Avrampou K, Shi H, Tabas I. Schilperoort M, et al. Among authors: tabas i. Immunol Rev. 2023 Oct;319(1):65-80. doi: 10.1111/imr.13214. Epub 2023 May 9. Immunol Rev. 2023. PMID: 37158427 Review.

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