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Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Zhu X, et al. Among authors: szweda li, szweda pa. Free Radic Biol Med. 2012 Feb 1;52(3):699-704. doi: 10.1016/j.freeradbiomed.2011.11.004. Epub 2011 Nov 12. Free Radic Biol Med. 2012. PMID: 22137893 Free PMC article.
High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal.
Wataya T, Nunomura A, Smith MA, Siedlak SL, Harris PL, Shimohama S, Szweda LI, Kaminski MA, Avila J, Price DL, Cleveland DW, Sayre LM, Perry G. Wataya T, et al. Among authors: szweda li. J Biol Chem. 2002 Feb 15;277(7):4644-8. doi: 10.1074/jbc.M110913200. Epub 2001 Dec 3. J Biol Chem. 2002. PMID: 11733539 Free article.
Increased autophagic degradation of mitochondria in Alzheimer disease.
Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Moreira PI, et al. Among authors: szweda li. Autophagy. 2007 Nov-Dec;3(6):614-5. doi: 10.4161/auto.4872. Epub 2007 Aug 14. Autophagy. 2007. PMID: 17786024
Proteolysis, free radicals, and aging.
Szweda PA, Friguet B, Szweda LI. Szweda PA, et al. Among authors: szweda li. Free Radic Biol Med. 2002 Jul 1;33(1):29-36. doi: 10.1016/s0891-5849(02)00837-7. Free Radic Biol Med. 2002. PMID: 12086679 Review.
α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor.
McLain AL, Szweda PA, Szweda LI. McLain AL, et al. Among authors: szweda li, szweda pa. Free Radic Res. 2011 Jan;45(1):29-36. doi: 10.3109/10715762.2010.534163. Epub 2010 Nov 29. Free Radic Res. 2011. PMID: 21110783 Free PMC article. Review.
Autophagocytosis of mitochondria is prominent in Alzheimer disease.
Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Moreira PI, et al. Among authors: szweda li. J Neuropathol Exp Neurol. 2007 Jun;66(6):525-32. doi: 10.1097/01.jnen.0000240476.73532.b0. J Neuropathol Exp Neurol. 2007. PMID: 17549012
Aging: a shift from redox regulation to oxidative damage.
Humphries KM, Szweda PA, Szweda LI. Humphries KM, et al. Among authors: szweda li, szweda pa. Free Radic Res. 2006 Dec;40(12):1239-43. doi: 10.1080/10715760600913184. Free Radic Res. 2006. PMID: 17090412 Review.
135 results