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A year-long extended release nanoformulated cabotegravir prodrug.
Kulkarni TA, Bade AN, Sillman B, Shetty BLD, Wojtkiewicz MS, Gautam N, Hilaire JR, Sravanam S, Szlachetka A, Lamberty BG, Morsey BM, Fox HS, Alnouti Y, McMillan JM, Mosley RL, Meza J, Domanico PL, Yue TY, Moore G, Edagwa BJ, Gendelman HE. Kulkarni TA, et al. Among authors: szlachetka a. Nat Mater. 2020 Aug;19(8):910-920. doi: 10.1038/s41563-020-0674-z. Epub 2020 Apr 27. Nat Mater. 2020. PMID: 32341511 Free PMC article.
Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles.
Zhou T, Su H, Dash P, Lin Z, Dyavar Shetty BL, Kocher T, Szlachetka A, Lamberty B, Fox HS, Poluektova L, Gorantla S, McMillan J, Gautam N, Mosley RL, Alnouti Y, Edagwa B, Gendelman HE. Zhou T, et al. Among authors: szlachetka a. Biomaterials. 2018 Jan;151:53-65. doi: 10.1016/j.biomaterials.2017.10.023. Epub 2017 Oct 15. Biomaterials. 2018. PMID: 29059541 Free PMC article.
Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques.
McMillan J, Szlachetka A, Slack L, Sillman B, Lamberty B, Morsey B, Callen S, Gautam N, Alnouti Y, Edagwa B, Gendelman HE, Fox HS. McMillan J, et al. Among authors: szlachetka a. Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01316-17. doi: 10.1128/AAC.01316-17. Print 2018 Jan. Antimicrob Agents Chemother. 2017. PMID: 29061742 Free PMC article.
Creation of a long-acting rilpivirine prodrug nanoformulation.
Hilaire JR, Bade AN, Sillman B, Gautam N, Herskovitz J, Dyavar Shetty BL, Wojtkiewicz MS, Szlachetka A, Lamberty BG, Sravanam S, Fox HS, Alnouti Y, Dash PK, McMillan JM, Edagwa BJ, Gendelman HE. Hilaire JR, et al. Among authors: szlachetka a. J Control Release. 2019 Oct;311-312:201-211. doi: 10.1016/j.jconrel.2019.09.001. Epub 2019 Sep 3. J Control Release. 2019. PMID: 31491432 Free PMC article.
Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation.
Deodhar S, Sillman B, Bade AN, Avedissian SN, Podany AT, McMillan JM, Gautam N, Hanson B, Dyavar Shetty BL, Szlachetka A, Johnston M, Thurman M, Munt DJ, Dash AK, Markovic M, Dahan A, Alnouti Y, Yazdi A, Kevadiya BD, Byrareddy SN, Cohen SM, Edagwa B, Gendelman HE. Deodhar S, et al. Among authors: szlachetka a. Nat Commun. 2022 Jun 9;13(1):3226. doi: 10.1038/s41467-022-30902-7. Nat Commun. 2022. PMID: 35680875 Free PMC article.
Antiretroviral drug-S for a possible HIV elimination.
Agas A, Schuetz H, Mishra V, Szlachetka AM, Haorah J. Agas A, et al. Among authors: szlachetka am. Int J Physiol Pathophysiol Pharmacol. 2019 Aug 15;11(4):149-162. eCollection 2019. Int J Physiol Pathophysiol Pharmacol. 2019. PMID: 31523362 Free PMC article.
Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain.
Rump TJ, Abdul Muneer PM, Szlachetka AM, Lamb A, Haorei C, Alikunju S, Xiong H, Keblesh J, Liu J, Zimmerman MC, Jones J, Donohue TM Jr, Persidsky Y, Haorah J. Rump TJ, et al. Among authors: szlachetka am. Free Radic Biol Med. 2010 Nov 30;49(10):1494-504. doi: 10.1016/j.freeradbiomed.2010.08.011. Epub 2010 Aug 12. Free Radic Biol Med. 2010. PMID: 20708681 Free PMC article.
17 results