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84 results

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A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia.
Krystal AD, Pizzagalli DA, Smoski M, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu D, Murrough JW, Yang H, Weiner RD, Calabrese JR, Sanacora G, Hermes G, Keefe RSE, Song A, Goodman W, Szabo ST, Whitton AE, Gao K, Potter WZ. Krystal AD, et al. Among authors: szabo st. Nat Med. 2020 May;26(5):760-768. doi: 10.1038/s41591-020-0806-7. Epub 2020 Mar 30. Nat Med. 2020. PMID: 32231295 Free PMC article. Clinical Trial.
Amygdala Nuclei Volume and Shape in Military Veterans With Posttraumatic Stress Disorder.
Morey RA, Clarke EK, Haswell CC, Phillips RD, Clausen AN, Mufford MS, Saygin Z; VA Mid-Atlantic MIRECC Workgroup; Wagner HR, LaBar KS. Morey RA, et al. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Mar;5(3):281-290. doi: 10.1016/j.bpsc.2019.11.016. Epub 2019 Dec 14. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020. PMID: 32029420 Free PMC article.
The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development.
Krystal AD, Pizzagalli DA, Mathew SJ, Sanacora G, Keefe R, Song A, Calabrese J, Goddard A, Goodman W, Lisanby SH, Smoski M, Weiner R, Iosifescu D, Nurnberger J Jr, Szabo S, Murrough J, Shekhar A, Potter W. Krystal AD, et al. Nat Rev Drug Discov. 2018 Dec 28;18(1):82-84. doi: 10.1038/nrd.2018.222. Nat Rev Drug Discov. 2018. PMID: 30591715 Free PMC article. No abstract available.
A pilot randomized placebo-controlled trial of adjunctive aripiprazole for chronic PTSD in US military Veterans resistant to antidepressant treatment.
Naylor JC, Kilts JD, Bradford DW, Strauss JL, Capehart BP, Szabo ST, Smith KD, Dunn CE, Conner KM, Davidson JR, Wagner HR, Hamer RM, Marx CE. Naylor JC, et al. Among authors: szabo st. Int Clin Psychopharmacol. 2015 May;30(3):167-74. doi: 10.1097/YIC.0000000000000061. Int Clin Psychopharmacol. 2015. PMID: 25647451 Clinical Trial.
Reducing Suicidal Ideation Through Insomnia Treatment (REST-IT): A Randomized Clinical Trial.
McCall WV, Benca RM, Rosenquist PB, Youssef NA, McCloud L, Newman JC, Case D, Rumble ME, Szabo ST, Phillips M, Krystal AD. McCall WV, et al. Among authors: szabo st. Am J Psychiatry. 2019 Nov 1;176(11):957-965. doi: 10.1176/appi.ajp.2019.19030267. Epub 2019 Sep 20. Am J Psychiatry. 2019. PMID: 31537089 Free PMC article. Clinical Trial.
Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial.
Naylor JC, Kilts JD, Shampine LJ, Parke GJ, Wagner HR, Szabo ST, Smith KD, Allen TB, Telford-Marx EG, Dunn CE, Cuffe BT, O'Loughlin SH, Marx CE. Naylor JC, et al. Among authors: szabo st. JAMA Netw Open. 2020 Mar 2;3(3):e200287. doi: 10.1001/jamanetworkopen.2020.0287. JAMA Netw Open. 2020. PMID: 32119096 Free PMC article. Clinical Trial.
Practical telehealth to improve control and engagement for patients with clinic-refractory diabetes mellitus (PRACTICE-DM): Protocol and baseline data for a randomized trial.
Kobe EA, Edelman D, Tarkington PE, Bosworth HB, Maciejewski ML, Steinhauser K, Jeffreys AS, Coffman CJ, Smith VA, Strawbridge EM, Szabo ST, Desai S, Garrett MP, Wilmot TC, Marcano TJ, Overby DL, Tisdale GA, Durkee M, Bullard S, Dar MS, Mundy AC, Hiner J, Fredrickson SK, Majette Elliott NT, Howard T, Jeter DH, Danus S, Crowley MJ. Kobe EA, et al. Among authors: szabo st. Contemp Clin Trials. 2020 Nov;98:106157. doi: 10.1016/j.cct.2020.106157. Epub 2020 Sep 21. Contemp Clin Trials. 2020. PMID: 32971277 Free PMC article.
84 results