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Metabolic regulation in progression to autoimmune diabetes.
Sysi-Aho M, Ermolov A, Gopalacharyulu PV, Tripathi A, Seppänen-Laakso T, Maukonen J, Mattila I, Ruohonen ST, Vähätalo L, Yetukuri L, Härkönen T, Lindfors E, Nikkilä J, Ilonen J, Simell O, Saarela M, Knip M, Kaski S, Savontaus E, Orešič M. Sysi-Aho M, et al. PLoS Comput Biol. 2011 Oct;7(10):e1002257. doi: 10.1371/journal.pcbi.1002257. Epub 2011 Oct 27. PLoS Comput Biol. 2011. PMID: 22046124 Free PMC article.
Dietary carbohydrate modification alters serum metabolic profiles in individuals with the metabolic syndrome.
Lankinen M, Schwab U, Gopalacharyulu PV, Seppänen-Laakso T, Yetukuri L, Sysi-Aho M, Kallio P, Suortti T, Laaksonen DE, Gylling H, Poutanen K, Kolehmainen M, Oresic M. Lankinen M, et al. Nutr Metab Cardiovasc Dis. 2010 May;20(4):249-57. doi: 10.1016/j.numecd.2009.04.009. Epub 2009 Jun 23. Nutr Metab Cardiovasc Dis. 2010. PMID: 19553094 Clinical Trial.
Metabolome in progression to Alzheimer's disease.
Orešič M, Hyötyläinen T, Herukka SK, Sysi-Aho M, Mattila I, Seppänan-Laakso T, Julkunen V, Gopalacharyulu PV, Hallikainen M, Koikkalainen J, Kivipelto M, Helisalmi S, Lötjönen J, Soininen H. Orešič M, et al. Transl Psychiatry. 2011 Dec 13;1(12):e57. doi: 10.1038/tp.2011.55. Transl Psychiatry. 2011. PMID: 22832349 Free PMC article.
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes.
Oresic M, Simell S, Sysi-Aho M, Näntö-Salonen K, Seppänen-Laakso T, Parikka V, Katajamaa M, Hekkala A, Mattila I, Keskinen P, Yetukuri L, Reinikainen A, Lähde J, Suortti T, Hakalax J, Simell T, Hyöty H, Veijola R, Ilonen J, Lahesmaa R, Knip M, Simell O. Oresic M, et al. J Exp Med. 2008 Dec 22;205(13):2975-84. doi: 10.1084/jem.20081800. Epub 2008 Dec 15. J Exp Med. 2008. PMID: 19075291 Free PMC article.
Bioinformatics and computational methods for lipidomics.
Niemelä PS, Castillo S, Sysi-Aho M, Oresic M. Niemelä PS, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15;877(26):2855-62. doi: 10.1016/j.jchromb.2009.01.025. Epub 2009 Jan 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19200789 Review.
Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes.
Oresic M, Gopalacharyulu P, Mykkänen J, Lietzen N, Mäkinen M, Nygren H, Simell S, Simell V, Hyöty H, Veijola R, Ilonen J, Sysi-Aho M, Knip M, Hyötyläinen T, Simell O. Oresic M, et al. Diabetes. 2013 Sep;62(9):3268-74. doi: 10.2337/db13-0159. Epub 2013 Apr 29. Diabetes. 2013. PMID: 23630305 Free PMC article.
Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression.
Hilvo M, Denkert C, Lehtinen L, Müller B, Brockmöller S, Seppänen-Laakso T, Budczies J, Bucher E, Yetukuri L, Castillo S, Berg E, Nygren H, Sysi-Aho M, Griffin JL, Fiehn O, Loibl S, Richter-Ehrenstein C, Radke C, Hyötyläinen T, Kallioniemi O, Iljin K, Oresic M. Hilvo M, et al. Cancer Res. 2011 May 1;71(9):3236-45. doi: 10.1158/0008-5472.CAN-10-3894. Epub 2011 Mar 17. Cancer Res. 2011. PMID: 21415164
29 results