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Mechanism-Driven and Clinically Focused Development of Botanical Foods as Multitarget Anticancer Medicine: Collective Perspectives and Insights from Preclinical Studies, IND Applications and Early-Phase Clinical Trials.
Wang X, Chan YS, Wong K, Yoshitake R, Sadava D, Synold TW, Frankel P, Twardowski PW, Lau C, Chen S. Wang X, et al. Among authors: synold tw. Cancers (Basel). 2023 Jan 23;15(3):701. doi: 10.3390/cancers15030701. Cancers (Basel). 2023. PMID: 36765659 Free PMC article. Review.
Phase I trial of continuous infusion 5-aza-2'-deoxycytidine.
Aparicio A, Eads CA, Leong LA, Laird PW, Newman EM, Synold TW, Baker SD, Zhao M, Weber JS. Aparicio A, et al. Among authors: synold tw. Cancer Chemother Pharmacol. 2003 Mar;51(3):231-9. doi: 10.1007/s00280-002-0563-y. Epub 2003 Feb 27. Cancer Chemother Pharmacol. 2003. PMID: 12655442 Clinical Trial.
Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts.
Doroshow JH, Gaur S, Markel S, Lu J, van Balgooy J, Synold TW, Xi B, Wu X, Juhasz A. Doroshow JH, et al. Among authors: synold tw. Free Radic Biol Med. 2013 Apr;57:162-75. doi: 10.1016/j.freeradbiomed.2013.01.002. Epub 2013 Jan 11. Free Radic Biol Med. 2013. PMID: 23314043 Free PMC article.
Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use.
Metz MZ, Gutova M, Lacey SF, Abramyants Y, Vo T, Gilchrist M, Tirughana R, Ghoda LY, Barish ME, Brown CE, Najbauer J, Potter PM, Portnow J, Synold TW, Aboody KS. Metz MZ, et al. Among authors: synold tw. Stem Cells Transl Med. 2013 Dec;2(12):983-92. doi: 10.5966/sctm.2012-0177. Epub 2013 Oct 28. Stem Cells Transl Med. 2013. PMID: 24167321 Free PMC article.
Effect of valspodar on the pharmacokinetics of unbound paclitaxel.
ten Tije AJ, Synold TW, Spicer D, Verweij J, Doroshow JH, Sparreboom A. ten Tije AJ, et al. Among authors: synold tw. Invest New Drugs. 2003 Aug;21(3):291-8. doi: 10.1023/a:1025412509730. Invest New Drugs. 2003. PMID: 14578679 Clinical Trial.
Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
Galpin AJ, Schuetz JD, Masson E, Yanishevski Y, Synold TW, Barredo JC, Pui CH, Relling MV, Evans WE. Galpin AJ, et al. Among authors: synold tw. Mol Pharmacol. 1997 Jul;52(1):155-63. doi: 10.1124/mol.52.1.155. Mol Pharmacol. 1997. PMID: 9224825
139 results