Svensson R - Search Results

1

Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration.

Hellinen L, Koskela A, Vattulainen E, Liukkonen M, Wegler C, Treyer A, Handin N, Svensson R, Myöhänen T, Poso A, Kaarniranta K, Artursson P, Urtti A. Hellinen L, et al. Among authors: svensson r. Biomed Pharmacother. 2022 Feb;146:112501. doi: 10.1016/j.biopha.2021.112501. Epub 2021 Dec 7. Biomed Pharmacother. 2022. PMID: 34891119 Free article.

2

In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.

Karlgren M, Ahlin G, Bergström CA, Svensson R, Palm J, Artursson P. Karlgren M, et al. Among authors: svensson r. Pharm Res. 2012 Feb;29(2):411-26. doi: 10.1007/s11095-011-0564-9. Epub 2011 Aug 23. Pharm Res. 2012. PMID: 21861202 Free PMC article.

3

Optimizing solubility and permeability of a biopharmaceutics classification system (BCS) class 4 antibiotic drug using lipophilic fragments disturbing the crystal lattice.

Tehler U, Fagerberg JH, Svensson R, Larhed M, Artursson P, Bergström CA. Tehler U, et al. Among authors: svensson r. J Med Chem. 2013 Mar 28;56(6):2690-4. doi: 10.1021/jm301721e. Epub 2013 Mar 19. J Med Chem. 2013. PMID: 23432334 Free article.

4

Preclinical characterization of acyl sulfonimidamides: potential carboxylic acid bioisosteres with tunable properties.

Borhade SR, Svensson R, Brandt P, Artursson P, Arvidsson PI, Sandström A. Borhade SR, et al. Among authors: svensson r. ChemMedChem. 2015 Mar;10(3):455-60. doi: 10.1002/cmdc.201402497. Epub 2015 Jan 28. ChemMedChem. 2015. PMID: 25630705

5

Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles.

Lampa A, Alogheli H, Ehrenberg AE, Åkerblom E, Svensson R, Artursson P, Danielson UH, Karlén A, Sandström A. Lampa A, et al. Among authors: svensson r. Bioorg Med Chem. 2014 Dec 1;22(23):6595-6615. doi: 10.1016/j.bmc.2014.10.010. Bioorg Med Chem. 2014. PMID: 25456385

6

Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound.

Islam MK, Strand M, Saleeb M, Svensson R, Baranczewski P, Artursson P, Wadell G, Ahlm C, Elofsson M, Evander M. Islam MK, et al. Among authors: svensson r. Sci Rep. 2018 Jan 31;8(1):1925. doi: 10.1038/s41598-018-20362-9. Sci Rep. 2018. PMID: 29386590 Free PMC article.

7

Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity.

Good JA, Silver J, Núñez-Otero C, Bahnan W, Krishnan KS, Salin O, Engström P, Svensson R, Artursson P, Gylfe Å, Bergström S, Almqvist F. Good JA, et al. Among authors: svensson r. J Med Chem. 2016 Mar 10;59(5):2094-108. doi: 10.1021/acs.jmedchem.5b01759. Epub 2016 Feb 22. J Med Chem. 2016. PMID: 26849778

8

Structure-activity relationships for lipoprotein lipase agonists that lower plasma triglycerides in vivo.

Caraballo R, Larsson M, Nilsson SK, Ericsson M, Qian W, Nguyen Tran NP, Kindahl T, Svensson R, Saar V, Artursson P, Olivecrona G, Enquist PA, Elofsson M. Caraballo R, et al. Among authors: svensson r. Eur J Med Chem. 2015 Oct 20;103:191-209. doi: 10.1016/j.ejmech.2015.08.058. Epub 2015 Sep 2. Eur J Med Chem. 2015. PMID: 26355531 Free article.

9

Constrained H-Phe-Phe-NH2 analogues with high affinity to the substance P 1-7 binding site and with improved metabolic stability and cell permeability.

Fransson R, Sköld C, Kratz JM, Svensson R, Artursson P, Nyberg F, Hallberg M, Sandström A. Fransson R, et al. Among authors: svensson r. J Med Chem. 2013 Jun 27;56(12):4953-65. doi: 10.1021/jm400209h. Epub 2013 Jun 17. J Med Chem. 2013. PMID: 23735006 Free article.

10

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy.

Rendo V, Stoimenov I, Mateus A, Sjöberg E, Svensson R, Gustavsson AL, Johansson L, Ng A, OʼBrien C, Giannakis M, Artursson P, Nygren P, Cheong I, Sjöblom T. Rendo V, et al. Among authors: svensson r. Nat Commun. 2020 Mar 11;11(1):1308. doi: 10.1038/s41467-020-15111-4. Nat Commun. 2020. PMID: 32161261 Free PMC article.

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