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Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice.
Amor M, Bianco V, Buerger M, Lechleitner M, Vujić N, Dobrijević A, Akhmetshina A, Pirchheim A, Schwarz B, Pessentheiner AR, Baumgartner F, Rampitsch K, Schauer S, Klobučar I, Degoricija V, Pregartner G, Kummer D, Svecla M, Sommer G, Kolb D, Holzapfel GA, Hoefler G, Frank S, Norata GD, Kratky D. Amor M, et al. Among authors: svecla m. Cardiovasc Diabetol. 2023 Nov 28;22(1):327. doi: 10.1186/s12933-023-02064-3. Cardiovasc Diabetol. 2023. PMID: 38017481 Free PMC article.
The inhibition of inner mitochondrial fusion in hepatocytes reduces non-alcoholic fatty liver and improves metabolic profile during obesity by modulating bile acid conjugation.
Da Dalt L, Moregola A, Svecla M, Pedretti S, Fantini F, Ronzio M, Uboldi P, Dolfini D, Donetti E, Baragetti A, Mitro N, Scorrano L, Norata GD. Da Dalt L, et al. Among authors: svecla m. Cardiovasc Res. 2024 Feb 17;119(18):2917-2929. doi: 10.1093/cvr/cvad169. Cardiovasc Res. 2024. PMID: 37922889
Neutrophil aging exacerbates high fat diet induced metabolic alterations.
Baragetti A, Da Dalt L, Moregola A, Svecla M, Terenghi O, Mattavelli E, De Gaetano LN, Uboldi P, Catapano AL, Norata GD. Baragetti A, et al. Among authors: svecla m. Metabolism. 2023 Jul;144:155576. doi: 10.1016/j.metabol.2023.155576. Epub 2023 Apr 26. Metabolism. 2023. PMID: 37116643 Free article.
The low-density lipoprotein receptor-mTORC1 axis coordinates CD8+ T cell activation.
Bonacina F, Moregola A, Svecla M, Coe D, Uboldi P, Fraire S, Beretta S, Beretta G, Pellegatta F, Catapano AL, Marelli-Berg FM, Norata GD. Bonacina F, et al. Among authors: svecla m. J Cell Biol. 2022 Nov 7;221(11):e202202011. doi: 10.1083/jcb.202202011. Epub 2022 Sep 21. J Cell Biol. 2022. PMID: 36129440 Free PMC article.
14 results